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Investigating rDNA dysregulation in cancer: Unraveling chromosomal rearrangements and breakage consequences on rDNA activity, ribosome biogenesis, and

Organization UKRILocation United Kingdom
UKRIUK ResearchGrantActive
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Ribosomal-DNA (rDNA) repeats are essential DNA elements within our genome that produce ribosomal RNA, the building blocks of ribosomes, the sysnthesis of which is universally upregulated in cancer. Genetic alterations in rDNA have been implicated in various cancers, however the study of these alterations in cancer has been technically challenging…

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Investigating rDNA dysregulation in cancer: Unraveling chromosomal rearrangements and breakage consequences on rDNA acti | Dev Procure