grant
Inter-System Closed-Loop Control of Locomotor and Bladder Function in Individuals with Acute Spinal Cord Injury
Organization KESSLER FOUNDATION, INC.Location East Hanover, UNITED STATESPosted 15 Sept 2020Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY2024Activities of Daily LivingActivities of everyday lifeAcuteAddressAutonomic DysreflexiaAutonomic HyperreflexiaAutonomic nervous systemAwarenessBP controlBP homeostasisBP managementBP regulationBladderBladder Urinary SystemBlood PressureBlood Pressure MonitorsCardiac ChronotropismCardiovascularCardiovascular Body SystemCardiovascular Organ SystemCardiovascular systemCatheterizationChronicChronic PhaseClinical TrialsCommunicationCommunitiesContinuous SphygmomanometersDataDevelopmentDevicesDiastolic PressureDiastolic blood pressureEducation for InterventionEducational InterventionEvaluationFeedbackHeart RateHeart VascularHomeImpairmentImplantIncidenceIndividualInjuryInstruction InterventionIntestinalIntestinesLaboratoriesLocomotionLocomotor trainingManualsMeasuresMedulla SpinalisMonitorMotorMovementParticipantPatientsPersonsPhasePhysiologicPhysiologicalPositionPositioning AttributePublishingQOLQuality of lifeRainRandomizedRecoveryRegulationReportingSeriesSpinal Autonomic DysreflexiaSpinal CordSpinal Cord TraumaSpinal TraumaSpinal cord injuredSpinal cord injurySymptomsSystemSystolic PressureTechnologyTestingTimeTrainingTraining InterventionTraining ProgramsTraumatic MyelopathyUnited StatesWalkingblood pressure controlblood pressure homeostasisblood pressure managementblood pressure regulationbody movementbowelcirculatory systemdaily living functiondaily living functionalitydesigndesigningdevelopmentalexperienceflexibilityflexiblefunctional abilityfunctional capacityhomesimplementation facilitationimprovedinjuriesinstructional interventionintimacyintimate behaviorlearning algorithmlocomotor controllocomotor tasksmotor function recoveryneural circuitneural circuitryneural controlneural regulationneurocircuitryneuromodulationneuromodulatoryneuroregulationnormotensiveprediction algorithmpreventpreventingrainfallrandomisationrandomizationrandomly assignedrecovered motor functionregulate BPregulate blood pressuresensorsensory systemsynaptic circuitsynaptic circuitrytherapeutic evaluationtherapeutic testingtooltreadmilltreatment effecturinary bladderwireless communicationwireless monitorwireless sensor
Description preview
SUMMARY ABSTRACT
More than 1.2 million people in the United States have a spinal cord injury (SCI), and each year there are 10,000
new cases. In the last few years, we have shown that neuromodulation using epidural stimulation of the
lumbosacral spinal cord can activate latent neural circuits and restore voluntary movement, standing and
stepping…
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