grant
Integrative biophysical modeling for collective tissue mechanics
Organization NORTHEASTERN UNIVERSITYLocation BOSTON, UNITED STATESPosted 1 Sept 2023Deadline 31 Aug 2028
NIHUS FederalResearch GrantFY20252-dimensional3-D3-Dimensional3DAddressAffectAlveolusBehaviorBiomechanicsBiophysicsBody TissuesBronchial AlveolusCell BodyCellsCellular biologyComputer ModelsComputerized ModelsCuesDevelopmentEmbryoEmbryo DevelopmentEmbryogenesisEmbryonicEmbryonic DevelopmentEndothelial CellsEpidermisEpithelial CellsEpitheliumEventGeometryLengthLiquid substanceMeasurementMechanicsModelingMorphogenesisMorphologyNuclearOrganOrganism-Level ProcessOrganismal ProcessPhysiologic ProcessesPhysiological ProcessesProliferatingRadialRadiusRheologyRoleSolidStructureSurfaceSystemTheoretic ModelsTheoretical modelTimeTissuesTubebiomechanic modelingbiomechanic simulationbiomechanicalbiomechanical modelbiomechanical modelingbiomechanical simulationbiophysical foundationbiophysical modelbiophysical principlesbiophysical sciencescell behaviorcell biologycellular behaviorcomputational modelingcomputational modelscomputer based modelscomputerized modelingdevelopmentalfluidliquidmechanicmechanicalmonolayermorphogenetic processnovelphysical modelrepairrepairedsocial rolethree dimensionaltwo-dimensional
Description preview
Project Summary/Abstract
Organ surfaces are covered with epithelial cells or endothelial cells, providing physical barriers for organs and
bodies. Cells on these confluent layers often remain static and non-migratory. However, they can also undergo
active structural rearrangements during basic physiological processes ranging across embryonic…
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