grant
Integrating genetic and ecological momentary assessment technologies to advance models of PTSD-AUD comorbidity
Organization VIRGINIA COMMONWEALTH UNIVERSITYLocation RICHMOND, UNITED STATESPosted 1 Sept 2023Deadline 31 Aug 2028
NIHUS FederalResearch GrantFY2025AccountingActive Follow-upAcuteAddressAffectAlcohol DrinkingAlcohol PhenotypeAlcohol consumptionAreaBlack PopulationsBlack groupBlack individualBlack peopleBlacksCOVID crisisCOVID epidemicCOVID pandemicCOVID-19 crisisCOVID-19 epidemicCOVID-19 eraCOVID-19 global health crisisCOVID-19 global pandemicCOVID-19 health crisisCOVID-19 pandemicCOVID-19 periodCOVID-19 public health crisisCOVID-19 yearsCausalityClinicalConsumptionDataDecrease health disparitiesDevelopmentDiagnosticDiseaseDisorderDisparitiesDisparityDropoutEcological momentary assessmentEconomicsEnrollmentEquationEquityEtOH drinkingEtOH useEtiologyFinancial HardshipGWA studyGWASGeneticGenetic ResearchGenetic RiskGenetic studyGenomicsGoalsGroups at riskHealthHealth disparity mitigationHealth disparity reductionHeritabilityHistoryIndividualInterventionInterviewInvestigationKnowledgeLeadLightLower health disparitiesMeasurementMeasuresMental HealthMental HygieneMethodologyMethodsMitigate health disparitiesModelingMolecular GeneticsPTSDParticipantPathway interactionsPatient RecruitmentsPatient Self-ReportPb elementPeople at riskPersonsPersons at riskPhenotypePhotoradiationPopulationPopulations at RiskPost-Traumatic NeurosesPost-Traumatic Stress DisordersPosttraumatic NeurosesPredispositionPrevalencePreventionPrevention programPrognosisProtocolProtocols documentationPsychological HealthPublic HealthRecording of previous eventsReduce health disparitiesResearchResearch ResourcesResourcesRiskRisk BehaviorsRisk FactorsRisky BehaviorSARS-CoV-2 epidemicSARS-CoV-2 global health crisisSARS-CoV-2 global pandemicSARS-CoV-2 pandemicSARS-coronavirus-2 epidemicSARS-coronavirus-2 pandemicSamplingSelf MedicationSelf-ReportSeriesSevere Acute Respiratory Syndrome CoV 2 epidemicSevere Acute Respiratory Syndrome CoV 2 pandemicSevere acute respiratory syndrome coronavirus 2 epidemicSevere acute respiratory syndrome coronavirus 2 pandemicSeveritiesSocial supportSpecificitySusceptibilitySymptomsTechnology AssessmentTestingTimeTraumaUnderrepresented GroupsUnderrepresented PopulationsUrban CommunityUrban PopulationVariantVariationWomanWorkactive followupalcohol ingestionalcohol intakealcohol product usealcohol riskalcohol usealcohol use disorderalcoholic beverage consumptionalcoholic drink intakealcoholic phenotypeat risk behaviorbinge alcohol consumptionbinge drinkingcausationco-morbidco-morbiditycomorbiditycoronavirus disease 2019 crisiscoronavirus disease 2019 epidemiccoronavirus disease 2019 global health crisiscoronavirus disease 2019 global pandemiccoronavirus disease 2019 health crisiscoronavirus disease 2019 pandemiccoronavirus disease 2019 public health crisiscoronavirus disease crisiscoronavirus disease epidemiccoronavirus disease pandemiccoronavirus disease-19 global pandemiccoronavirus disease-19 pandemiccravingdesigndesigningdevelopmentaldiscrimination based on racediscrimination due to racedisease causationdisparity gapeconomicenrollepisodic drinkingequity gapethanol consumptionethanol drinkingethanol ingestionethanol intakeethanol product useethanol useethanol use disorderexposure to traumafinancial adversityfinancial burdenfinancial distressfinancial insecurityfinancial strainfinancial stressfollow upfollow up assessmentfollow-upfollowed upfollowupfollowup assessmentgap in equitygap in inequalitygap in inequitygenome wide analysisgenome wide associationgenome wide association scangenome wide association studygenome wide studiesgenome-wide analysisgenome-wide identificationgenomewide association scangenomewide association studygroup of colorheavy metal Pbheavy metal leadhigh riskhistoriesindexingindividual of colorinequality gapinequitable gapinequity gapinner cityknowledge baselongitudinal designlongitudinal experimental designlongitudinal research designlongitudinal study designlow SESlow socio-economic positionlow socio-economic statuslow socioeconomic positionlow socioeconomic statusmennovelpandemicpandemic diseaseparticipant recruitmentpathwaypeople of colorperson of colorpolygenetic risk scorespolygenic risk scorepopulation of colorpost-trauma stress disorderposttrauma stress disorderprospectiveprotective factorsrace discriminationrace-based discriminationrace-related discriminationracial discriminationracial minorityracial minority groupracial minority individualracial minority peopleracial minority populationrelapse riskrisk sharingsaliva samplesalivary samplesevere acute respiratory syndrome coronavirus 2 global health crisissevere acute respiratory syndrome coronavirus 2 global pandemicsexsocialsocial health determinantssocial support networktrauma exposuretraumatic neurosistreatment programunder representation of groupsunder represented groupsunder represented peopleunder represented populationsunderrepresentation of groupsunderrepresented peopleurban groupurban individualurban peoplewhole genome association analysiswhole genome association study
Description preview
Project Summary
Alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD) commonly co-occur, and this comorbidity
is associated with higher consumption, treatment dropout, and risk for relapse. Urban populations of low
socioeconomic status are particularly at risk for AUD and PTSD. Research on the etiology of co-occurring AUD
and PTSD is…
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