grant
Influence of Interpersonal Connectedness in Spousal Care Dyads on Early Progression of AD
Organization UNIVERSITY OF NEBRASKA MEDICAL CENTERLocation OMAHA, UNITED STATESPosted 15 Sept 2025Deadline 14 Sept 2029
NIHUS FederalResearch GrantFY2025AD dementiaAPOE e4APOE-ε4APOEε4Active Follow-upAddressAlzheimer Type DementiaAlzheimer disease dementiaAlzheimer risk factorAlzheimer sclerosisAlzheimer syndromeAlzheimer'sAlzheimer's DiseaseAlzheimer's disease riskAlzheimers DementiaAmentiaBehaviorBeliefCare GiversCaregiversCaringCharacteristicsClinicClinicalCodeCoding SystemCommunitiesDementiaDementia caregiversDigital biomarkerDiscipline of NursingDiseaseDisease ManagementDisease ProgressionDisorderDisorder ManagementDisparitiesDisparityDrugsEarly identificationEmotionalEventFamilyFriendsGeneticGeographyGoalsHealthHealth BenefitHomeInterventionInterviewLaboratoriesLate Onset Alzheimer DiseaseLinkLongitudinal StudiesMarried PersonsMeasurementMeasuresMediatingMedicationMental HealthMental HygieneMethodsModelingMonitorMovementNebraskaNeurologyNursingNursing FieldNursing ProfessionOutcomeOutcome StudyPersonal SatisfactionPersonalityPersonsPharmaceutical PreparationsPrimary Senile Degenerative DementiaPrivacyPsychological HealthPsychologyPsychosocial FactorQOCQOLQuality of CareQuality of lifeQuestionnairesResearchResearch Project SummariesResearch ResourcesResourcesRoleRuralRural CommunityRural PopulationRural groupRural peopleScienceSecuritySelf EfficacySocial InteractionSocial supportSpouse CaregiverSpousesSurvival RateSymptomsTauopathiesTestingUncertaintyUrban Communityactive followupalzheimer riskapo E-4apo E4apo epsilon4apoE epsilon 4apoE-4apoE4apolipoprotein E epsilon 4apolipoprotein E-4apolipoprotein E4body movementbrain volumecare givingcare receivercare recipientscaregivers for persons living with dementiacaregivers for persons with dementiacaregivers of individuals with dementiacaregivers of patients with dementiacaregivingcognitive functiondata captured from wearablesdata collected from wearablesdata collected using wearablesdata gathered from wearabledata gathered through wearablesdata gathered via wearabledementia care giverdesigndesigningdigitaldigital markerdoubtdrug/agenteffective interventionexperiencefollow upfollow-upfollowed upfollowuphomesimprovedinterestlate onset alzheimerlong-term studylongitudinal designlongitudinal experimental designlongitudinal outcome studieslongitudinal research designlongitudinal study designneuropathologic tauneuropathological taunovelpositive emotionpositive emotional statepractice-based research networkprimary care practiceprimary degenerative dementiaprotective factorspsychosocial variablesrecruitrural arearural individualrural locationrural regionsenile dementia of the Alzheimer typesocial factorssocial rolesocial support networkspousal care giverspousal caregiverspouse care giverstress bufferingstress managementtau associated neurodegenerationtau associated neurodegenerative processtau driven neurodegenerationtau induced degenerationtau induced neurodegenerationtau mediated neurodegenerationtau neurodegenerative diseasetau neuropathologytau pathologytau pathophysiologytau proteinopathytau related neurodegenerationtau-induced pathologytauopathic neurodegenerative disordertauopathytheoriesurban areaurban locationurban regionwearablewearable datawearable devicewearable device datawearable electronicswearable sensor datawearable systemwearable technologywearable toolwearableswell-beingwellbeing
Description preview
PROJECT SUMMARY
Research on factors influencing the early progression of Alzheimer’s disease (AD) has primarily
focused on persons with dementia (PWD), such as their genetics. Most PWDs live within their
communities, and many maintain close connections with their spousal caregivers (CGs). Relationship
science research has shown that close…
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