grant
Individual cell bioprinting to generate multi-tissue type condensations for osteochondral tissue regeneration
Organization UNIVERSITY OF ILLINOIS AT CHICAGOLocation Chicago, UNITED STATESPosted 5 Apr 2023Deadline 29 Feb 2028
NIHUS FederalResearch GrantFY20253-D3-D print3-D printer3-D structure3-Dimensional3-dimensional structure3D3D Print3D printer3D printing3D structureAddressAffectAlginatesArchitectureBathingBathsBiological MimeticsBiomimeticsBlood VesselsBody TissuesCartilageCartilaginous TissueCell BodyCell CommunicationCell InteractionCell-to-Cell InteractionCellsChemicalsClinicalCommunitiesComplexDefectDegenerative ArthritisDegenerative polyarthritisDomestic RabbitEndothelial CellsEngineeringEngineering / ArchitectureEvaluationFaceFibrocartilagesFunctional RegenerationGelGeometryGrowth AgentsGrowth FactorGrowth SubstancesHealthHumanHydrogelsImmuneImmunesIndividualInferiorInflammatoryInvestigatorsKneeLeannessLiquid substanceLocationMaintenanceMechanicsMesenchymal Progenitor CellMesenchymal Stem CellsMesenchymal progenitorMesenchymal stromal/stem cellsModelingModern ManModificationMovementOperative ProceduresOperative Surgical ProceduresOrthopedicOrthopedic Surgical ProfessionOrthopedicsOryctolagus cuniculusOsteoarthritisOsteoarthrosisPatientsPersonsPhasePhenotypePhysical condensationPositionPositioning AttributePrintingProceduresProgenitor CellsPropertyProteins Growth FactorsRabbitsRabbits MammalsReactionResearch PersonnelResearchersResolutionRoleShapesSolidStructureSurgicalSurgical InterventionsSurgical ProcedureTechniquesTechnologyTherapeuticThickThicknessThinnessTissue EngineeringTissue constructsTissuesVascularizationVasculogenicbio-printingbioengineered tissuebioinkbiomaterial scaffoldbioprintingbioscaffoldbody movementbonebone repaircartilage repaircartilaginouscondensationdegenerative joint diseasedesigndesigningendothelial progenitorendothelial progenitor cellendothelial stem cellengineered tissuefacesfacialfibrocartilaginousfluidhealinghuman progenitorhuman stem cellshypertrophic arthritisimprovedin vivoinjury to tissueinnovateinnovationinnovativeliquidmechanicmechanicalmesenchymal stromal cellmesenchymal stromal progenitor cellsmesenchymal-derived stem cellsnovelosteochondralosteochondral tissueosteogenicparticlephysical propertyregenerate new tissueregenerate tissueregenerating damaged tissueregenerating tissuerepairrepairedresolutionsscaffoldscaffoldingsocial rolespatial and temporalspatial temporalspatiotemporalstandard of carestem cellssurgerythree dimensionalthree dimensional printingthree dimensional structuretissue injurytissue regenerationtissue regrowthtissue renewaltissue specific regenerationvascular
Description preview
Abstract
Osteochondral defects of the knee are common worldwide, yet there are few viable options for patients with
damaged osteochondral tissue as current treatments do not consistently regenerate functional tissue. The
standard of care for osteochondral defect repair is arthroscopic microfracture surgery, but this procedure often
results in…
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