grant
Improving Perioperative Care for Patients with Opioid Tolerance
Organization UNIVERSITY OF MICHIGAN AT ANN ARBORLocation ANN ARBOR, UNITED STATESPosted 15 Jul 2024Deadline 30 Apr 2029
NIHUS FederalResearch GrantFY202621+ years oldAcute PainAcute pain managementAcutely painfulAddressAdultAdult HumanAffectAmericanAttentionBlue CrossBlue ShieldCalibrationCaringCase MixesCenters for Disease ControlCenters for Disease Control and PreventionCenters for Disease Control and Prevention (U.S.)ClassificationClinicalCommunicationConsumptionDataDevelopmentDoseEffectivenessElementsEnsureEventExpenditureExposure toFailureFundingGeographic FactorGeographyGoalsGuidelinesHealthHealth CareHealth Care UtilizationHigh PrevalenceHospitalsHybridsIndividualInfrastructureInterventionInterviewKnowledgeLength of StayMeasuresMediatingMichiganMorbidity - disease rateNaloxoneNarcanNarcantiNumber of Days in HospitalOperative ProceduresOperative Surgical ProceduresOpiatesOpioidOutcomePainPain ControlPain TherapyPain managementPainfulPathway interactionsPatient CarePatient Care DeliveryPatient Outcomes AssessmentsPatient Reported MeasuresPatient Reported OutcomesPatient Self-ReportPatient outcomePatient-Centered OutcomesPatient-Focused OutcomesPatientsPerioperativePerioperative CarePerioperative complicationPerioperative painPost-operative PainPostoperativePostoperative PainPostoperative PeriodPrevalenceProspective StudiesProviderRE-AIMRandomization trialRandomizedReach, Effectiveness, Adoption, Implementation, and MaintenanceRecoveryReportingRespiratory DepressionRiskSamplingSelf-ReportStructureSurgicalSurgical InterventionsSurgical ProcedureSystematicsTestingUnited StatesUnited States Centers for Disease ControlUnited States Centers for Disease Control and PreventionVentilatory DepressionVulnerable PopulationsWorkWritingadulthoodassess effectivenesscare as usualcare coordinationcare for patientscare of patientscaring for patientsclinical careclinician factorsclinician-level factorsco-morbidco-morbiditycomorbiditycoordinating caredepressed breathingdepression of breathingdetermine effectivenessdevelopmentaldistribute naloxoneeffectiveness assessmenteffectiveness evaluationeffectiveness/implementation designeffectiveness/implementation hybrid designevaluate effectivenessevidence baseexamine effectivenessexperiencehealth care service usehealth care service utilizationhigh riskhospital carehospital dayshospital length of stayhospital re-admissionhospital readmissionhospital stayimprovedlicit opioidmorbidity ratemortalitynaloxone availabilitynaloxone dispensarynaloxone dispensationnaloxone dispensingnaloxone distributionnaloxone provisionnovelopiate consumptionopiate drug useopiate exposureopiate intakeopiate medicationopiate therapyopiate toleranceopiate useopioid consumptionopioid drug useopioid exposureopioid habituationopioid intakeopioid medicationopioid patientopioid therapyopioid toleranceopioid useoverdose riskpain after surgerypain interventionpain outcomepain reliefpain treatmentpain-related outcomepathwaypatient oriented outcomespatient tolerabilitypatient tolerancepatients who use opioidsphysician factorsphysician-level factorspost-surgical painpostsurgical painprescribed opiateprescribed opioidprescription opiateprescription opioidpreventpreventingprimary outcomeprogramsprospectiveprospective research studyprospective surveyprovide naloxoneprovider factorsprovider-level factorsrandomisationrandomizationrandomized trialrandomly assignedre-admissionre-hospitalizationreach, efficacy, adoption, implementation, and maintenancereadmissionrecruitrehospitalizationrelieve painrisk mitigationsatisfactionsecondary outcomesocio-demographic factorssociodemographic factorssurgerysurgery outcomesurgical outcometolerance to opiatestreatment as usualusual carevulnerable groupvulnerable individualvulnerable people
Description preview
In the United States, nearly 1 in 6 adults filled an opioid prescription in the past year and 10 million adults are
opioid tolerant. Compared with opioid naïve patients, individuals with opioid tolerance experience greater
challenges in managing acute pain especially after having surgery and poorer outcomes following surgical
care. For example,…
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