grant
Impact of Stretching on Tumor growth and Metastasis
Organization NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCHLocation UNITED STATES
NIHUS FederalResearch GrantFY20253D cell culture3D cultureAerobic ActivityAerobic ExerciseAerobic TrainingAerobic fitnessAnesthesiaAnesthesia proceduresAnimal BehaviorAnimal ModelAnimal Models and Related StudiesAnimalsApopainApoptosis-Related Cysteine Protease Caspase 3AreaAttentionBenignBiological MarkersBittner VirusBody TissuesBreast Cancer ModelBreast Cancer cell lineBreast NeoplasmsBreast TumorsBreast tumor cell lineBreast tumor modelCASP-3CASP3CASP3 geneCAT scanCPP-32CPP32CPP32 proteinCPP32BCPP32betaCT X RayCT XrayCT imagingCT scanCadherinsCancer ModelCancer PatientCancerModelCancersCell LineCell LocomotionCell MigrationCell MovementCell-Extracellular MatrixCellLineCellular MigrationCellular MotilityCollagenCollagen FiberComputed TomographyConnective TissueCrownsCysteine Protease CPP32Cysteine Protease CPP32 GeneDataDorsal PositionECMEstrogen ReceptorsExerciseExtracellular MatrixFVB MouseFiberFibrosisFlow CytofluorometriesFlow CytofluorometryFlow CytometryFlow MicrofluorimetryFlow MicrofluorometryFoodGelGenesHealthHomeHumanHydrogen OxideImageImplantInflammationInflammatory ResponseMMTVMalignant NeoplasmsMalignant TumorMammary CancerMammary Cancer VirusMammary NeoplasmsMeasuresMechanicsMediatorMetastasisMetastasis to the LungMetastasizeMetastatic LesionMetastatic MassMetastatic NeoplasmMetastatic Neoplasm to the LungMetastatic TumorMetastatic Tumor to the LungMiceMice MammalsModalityModelingModern ManMonitorMouse Mammary Tumor VirusMovementMurineMusNeoplasm MetastasisNon-pharmacologic TherapyNonpharmacologic InterventionNonpharmacologic TherapyNonpharmacologic approachNonpharmacologic treatmentPARP Cleavage ProteasePARP Cleavage Protease GenePersonal SatisfactionPhotonsPhysical activityPlasmidsPolyomaPolyoma VirusesPolyomavirusPrimary Cancer PreventionProductionProgesterone ReceptorsProgestin ReceptorsPyMTQi GongQigongRandomizedResolutionRheologyRodent ModelSCA-1SCA-1 GeneSREBP Cleavage Activity 1SREBP Cleavage Activity 1 GeneSecondary Cancer PreventionSecondary NeoplasmSecondary TumorStrains Cell LinesStretchingStructureSupine PositionSystemT'ai ChiTai ChiTai Chi ChihTai Chi ChuanTai JiTai Ji QuanTai QiTaiChiTaijiTaijiquanTechniquesTestingTissuesTomodensitometryTransgenesTransgenic ModelTumor ProcessTumor-Associated ProcessVisualizationWaterX-Ray CAT ScanX-Ray Computed TomographyX-Ray Computerized TomographyXray CAT scanXray Computed TomographyXray computerized tomographyYamaYama proteinYogabio-markersbiologic markerbiomarkerbody movementcancer metastasiscancer progressioncancer typecaspase-3catscancell motilitycomputed axial tomographycomputer tomographycomputerized axial tomographycomputerized tomographycultured cell linecysteine protease P32flow cytophotometryhomesimagingimproved mobilityin vitro Modelin vivo Modelinterestlung metastasismalignancymammary cancer modelmammary tumormammary tumor modelmanage symptommechanicmechanicalmetastasize to the lungmilk agentmobility enhancementmobility improvementmodel of animalneoplasm progressionneoplasm/cancerneoplastic progressionnon-contrast CTnon-drug therapynon-drug treatmentnoncontrast CTnoncontrast computed tomographynondrug therapynondrug treatmentoptimized mobilitypolyoma middle tumor antigenpulmonary metastasisrandomisationrandomizationrandomly assignedresolutionsscRNA sequencingscRNA-seqsecond harmonicsingle cell RNA-seqsingle cell RNAseqsingle cell expression profilingsingle cell transcriptomic profilingsingle-cell RNA sequencingspheroidssymptom managementthree dimensional cell culturetransgenetransgenic traittranslational opportunitiestranslational potentialtumortumor cell metastasistumor growthtumor progressionwell-beingwellbeing
Description preview
Cancer is among the most serious health problems worldwide, and this situation urges multiple efforts to develop new more effective and less toxic treatments. There has been interest in developing non-pharmacological treatments that could boost natural defenses against cancer and contribute to primary and secondary cancer prevention. Among…
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