grant
Impact of preadolescent psychostimulants on neurophysiology and sleep/wake disturbances
Organization CALIFORNIA STATE UNIV SAN BERNARDINOLocation SAN BERNARDINO, UNITED STATESPosted 23 Aug 2024Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY20250-11 years old21+ years oldAD/HDADHDAdolescentAdolescent DevelopmentAdolescent YouthAdultAdult HumanAnimal ModelAnimal Models and Related StudiesAnimalsArchitectureAttentionAttention deficit hyperactivity disorderBasic ResearchBasic ScienceBehaviorBrainBrain Nervous SystemChildChild YouthChildhoodChildren (0-21)Circadian DysregulationCircadian RhythmsClinical ResearchClinical StudyClinical TrialsCommon Rat StrainsComplementComplement ProteinsComplexConcertaDarknessDaytranaDevelopmentDiseaseDisinhibitionDisorderDrowsinessDrugsEEGElectroencephalogramElectroencephalographyEncephalonEngineering / ArchitectureEvent-Related PotentialsExhibitsFast-Wave SleepFundingGoalsGrantHigh PrevalenceHourHumanHyperactivityInbred SHR RatsInbred WKY RatsInbreedingIndividualInsomniaInsomnia DisorderLaboratory ResearchLightLinkLong-Term EffectsMedicationMetadateMethylphenidateModelingModern ManNervous System DiseasesNervous System DisorderNeurologic DisordersNeurological DisordersNyctohemeral RhythmParadoxical SleepPathologyPatientsPatternPharmaceutical AgentPharmaceutical PreparationsPharmaceuticalsPharmacologic SubstancePharmacological SubstancePhotoradiationPlayPopulationPredominantly Hyperactive-Impulsive Type Attention-Deficit DisorderPredominantly Hyperactive-Impulsive Type Hyperactivity DisorderREM SleepRatRat StrainsRats MammalsRattusResearchRhombencephalic SleepRitalinRodentRodent ControlRodent ModelRodentiaRodents MammalsRoleSHR RatsSleepSleep ArchitectureSleep DisordersSleep FragmentationsSleep disturbancesSleeplessnessSomnolenceSpontaneously Hypertensive RatsStimulantTechnologyTherapeuticTwenty-Four Hour RhythmWKY RatsWistar Kyoto Ratsaberrant sleepadult youthadulthoodbehavior measurementbehavioral measurebehavioral measurementcircadian abnormalitycircadian disruptioncircadian disturbancecircadian dysfunctioncircadian impairmentcircadian processcircadian rhythmicitycommon treatmentcomplementationdaily biorhythmdevelopmentaldisrupted sleepdisturbed sleepdreaming sleepdrug/agentevent related potentialexperienceexposure to psychostimulantsexposure to stimulantsfall asleepgirlsimpaired sleepimprovedinattentioninattentivenessinterestirregular sleepjuvenilejuvenile humankidslife spanlifespanmodel of animalneurological diseaseneurophysiologicalneurophysiologypediatricpeerpharmaceuticalpoor sleeppre-adolescentpre-clinical researchpre-clinical studypreadolescencepreclinical researchpreclinical studypredictive biological markerpredictive biomarkerspredictive markerpredictive molecular biomarkerpreteenpsychostimulantpsychostimulant exposurepsychostimulant usequality of sleeprapid eye movement sleepresponsesexsleep amountsleep diseasessleep disruptionsleep durationsleep dysfunctionsleep dysregulationsleep episodesleep illnesssleep intervalsleep lengthsleep onsetsleep patternsleep periodsleep problemsleep qualitysleep quantitysleep routinesleep schedulesleep timesleep/wake disruptionsleep/wake disturbancesleep/wake patternssleepinesssocial rolespontaneous hypertensive ratstimulant exposurestimulant usetime asleeptime during sleeptime in sleeptime spent asleeptime spent sleepingtranslational modeluse of stimulantsyoung adultyoung adult ageyoung adulthoodyoungster
Description preview
PROJECT SUMMARY
Children with attention-deficit/hyperactivity disorder (ADHD), whether taking stimulant medications or not,
experience more sleep problems than their peers. These nighttime sleep problems often lead to daytime
sleepiness, which is likely to exacerbate some of the negative behavior effects commonly associated with ADHD.
Since the…
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