grant
Impact of HIV and antiretroviral exposure in pregnancy on neurodevelopment and growth: leveraging a well-characterized cohort to gain novel and comprehensive insights
Organization MASSACHUSETTS GENERAL HOSPITALLocation BOSTON, UNITED STATESPosted 11 May 2026Deadline 30 Apr 2028
NIHUS FederalResearch GrantFY20260-11 years old3TC6 year old6 years of ageAIDS VirusAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusActive Follow-upAddressAnti-Retroviral AgentsAreaBirthBloodBlood Reticuloendothelial SystemBreast FeedingCells Placenta-TissueChildChild HealthChild YouthChildren (0-21)ClinicalCohort StudiesComplexDataData AnalysesData AnalysisDevelopmentDysfunctionEarly InterventionEarly identificationEnrollmentEnvironmental ExposureEnvironmental FactorEnvironmental Risk FactorExposure toFecesFunctional disorderGI microbiomeGeneralized GrowthGestationGoalsGrowthHIVHIV individualsHIV infected individualsHIV infected personsHIV peopleHIV positive individualsHIV positive peopleHairHealthHuman Immunodeficiency VirusesIndividualInfectionInterventionLAV-HTLV-IIILaboratoriesLamivudineLeast SquaresLeast-Squares AnalysesLeast-Squares AnalysisLifeLinkLongitudinal StudiesLongitudinal SurveysLymphadenopathy-Associated VirusMeasuresMediatingMediationMediatorMethodsModelingNational Institutes of HealthNegotiatingNegotiationNeural DevelopmentNeurodevelopmental DeficitNormal PlacentomaOutcomePLWHPWHParticipantParturitionPhysiopathologyPlacentaPlacenta Embryonic TissuePlacentomePopulationPositionPositioning AttributePrEPPregnancyPregnant WomenRegimenRiskSample SizeSamplingStatistical Data AnalysesStatistical Data AnalysisStatistical Data InterpretationStatistical MethodsTissue GrowthUgandaUnited States National Institutes of HealthVirus-HIVWorkactive followupadverse consequenceadverse outcomeage 6age 6 yearsanti-retroviralantiretroviral therapyantiretroviral treatmentco-exposuresco-morbidco-morbidityco-occurring exposurecohortcohort research studycohort surveycombined exposurecomorbiditycomplex exposureconcurrent exposuredata interpretationdevelopmentaldigestive tract microbiomeefavirenzenrollenteric microbiomeenvironmental riskexpectant motherexpectant womenexpecting motherexpecting womenexposed in uteroexposure mixtureexposure to environmental agentsexposure to environmental factorsexposure to environmental stimuliexposure to environmental substancesfetal exposurefollow upfollow-upfollowed upfollowupgastrointestinal microbiomegut microbiomegut-associated microbiomehealth dataimprovedimproved outcomein utero exposureindividuals infected with HIVindividuals who are pregnantindividuals with HIVindividuals with human immunodeficiency virusinsightintestinal biomeintestinal microbiomeintra-uterine environmental exposureintrauterine environmental exposurekidslarge data setslarge datasetslong-term studylongitudinal outcome studieslongitudinal research studymicrobiomemixed exposureneurodevelopmentnovelontogenypathophysiologypeerpeople infected with HIVpeople infected with human immunodeficiency viruspeople living with HIVpeople who are pregnantpeople with HIVpeople with human immunodeficiency viruspre-exposure prophylaxispregnant femalespregnant motherspregnant peoplepregnant populationsprenatal exposureprenatally exposedprospectivesimultaneous exposuressix year oldsix years of agesocial determinantssocial health determinantssocio-demographicssociodemographicssociodeterminantstatistic methodsstatistical analysisstoolthose who are pregnanttreatment effectwomen who are pregnantyoungster
Description preview
PROJECT SUMMARY
More than one million children who are HIV-exposed but uninfected (CHEU) are born to pregnant women with
HIV (PWHIV) every year. CHEU have poorer early-life outcomes than HIV-unexposed peers, including significant
neurodevelopmental deficits and a >2-fold risk of growth stunting. The pathophysiology and causes of adverse
CHEU…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click