grant
Immunomics Research Core
Organization LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTERLocation TORRANCE, UNITED STATESPosted 10 Aug 2023Deadline 31 May 2028
NIHUS FederalResearch GrantFY2025Anti-Infective AgentsAnti-Infective DrugsAnti-InfectivesAnti-infective PreparationAntibiotic AgentsAntibiotic DrugsAntibioticsAreaAssayBS-seqBioassayBioinformaticsBiological AssayBisulfite-based sequencingBloodBlood PlasmaBlood Reticuloendothelial SystemC albicansC. albicansC.albicansCUT&RUNCandidaCandida albicansCell BodyCell Culture TechniquesCellsCellular Immune FunctionChromatinCleavage Targets and Release Using NucleaseCleavage Under Targets and Release Using NucleaseConsensus SequenceDNADNA MethylationDNA-Protein InteractionDataData AnalysesData AnalysisData Management CoreData SetDeoxyribonucleic AcidDevelopmentEnhancersEnsureEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessExpression SignatureGene Expression ProfileGenerationsGeneticGenomeGenotypeGoalsGrantHospitalsImmuneImmune responseImmunesImmunoassayImmunologic SubtypingImmunophenotypingIn VitroInfectionInnate Immune ResponseLeadershipLibrariesLifeMRSAMacrophageMeasuresMethicillin Resistant S. AureusMicrobeMiscellaneous AntibioticMoniliaMφNGS MethodNGS systemOutcomePatient outcomePatient-Centered OutcomesPatient-Focused OutcomesPatientsPerformancePhenotypePlasmaPlasma SerumPreparationProtocolProtocols documentationPublishingR-Series Research ProjectsR01 MechanismR01 ProgramRNA SeqRNA sequencingRNAseqReagentResearchResearch GrantsResearch Project GrantsResearch ProjectsResearch SupportReticuloendothelial System, Serum, PlasmaRoleSamplingServicesShapesStandardizationSystemTechnical ExpertiseTechniquesTechnologyTestingadaptive immune responsebisulfite sequencingbisulfite-seqblood infectionbloodstream infectioncandidaemiacandidemiacell culturecell culturescell typecommunicable disease control agentcostdata exchangedata interpretationdata management and coordinating centerdata management centerdata transferdata transmissiondesigndesigningdevelopmentaldisease modeldisorder modelentire genomeepigeneticallyepigenomeepigenomicsexperimentexperimental researchexperimental studyexperimentsfull genomegene expression patterngene expression signatureglobal gene expressionglobal transcription profilehost responseimmune functionimmune system responseimmunological diversityimmunoresponseinfection in the bloodinfection of the bloodinnovateinnovationinnovativeinterestmethicillin resistance Staphylococcus aureusmethicillin resistant Staphylococcus aureusmethicillin resistant strains of Staphylococcus aureusmouse modelmurine modelnext gen sequencingnext generation sequencingnextgen sequencingpatient oriented outcomespreparationsprogramssocial roletechnical skillstranscriptional profiletranscriptional signaturetranscriptometranscriptome sequencingtranscriptomic sequencingtranscriptomicswhole genome
Description preview
IMMUNOMICS AND EPIGENOMICS CORE
PROJECT SUMMARY/ABSTRACT
The Immunomics and Epigenomics Core (IEC) is an essential component of the overall program that will
centralize the execution of a number of assays that will enable the characterization of immune responses. The
overall proposal aims to understand epigenetic changes in patients infected by…
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