grant
Imaging Feedback for Histotripsy Renal Tumor Ablation
Organization UNIVERSITY OF CHICAGOLocation CHICAGO, UNITED STATESPosted 1 Jul 2024Deadline 31 Mar 2028
NIHUS FederalResearch GrantFY2025AblationAcuteAddressAdoptionAgingAlgorithmsAnimal ModelAnimal Models and Related StudiesArtifactsAutomationBody TissuesCancersClinicalClinical EvaluationClinical TestingClinical TrialsCollaborationsCommon NeoplasmCommon TumorDetectionEchographyEchotomographyEnsureFamily suidaeFeedbackFocused Ultrasound AblationFocused Ultrasound TherapyFocused Ultrasound TreatmentGrawitz TumorHealth CareHepatic NeoplasmsHigh Power Focused UltrasoundHigh-intensity focused ultrasoundHypernephroid CarcinomaHypernephromaImageIn VitroKidneyKidney NeoplasmsKidney TumorKidney Urinary SystemLiver neoplasmsMalignantMalignant - descriptorMalignant NeoplasmsMalignant TumorMedical UltrasoundMethodsMiceMice MammalsModelingMonitorMorbidityMorbidity - disease rateMorphologic artifactsMsecMurineMusNephroid CarcinomaNewly DiagnosedOncologyOncology CancerOperative ProceduresOperative Surgical ProceduresOutcomePatientsPhysiologic pulsePigsPopulationProceduresPropertyProtocolProtocols documentationPulsePulse RatesQualifyingRenal AdenocarcinomaRenal Cell AdenocarcinomaRenal Cell CancerRenal Cell CarcinomaRenal NeoplasmsRenal TissueRenal TumorResearch SpecimenResolutionSafetyScheduleSourceSpecificitySpecimenSuidaeSurgicalSurgical InterventionsSurgical ProcedureSwineSystemTestingTimeTissuesTransducersTranslatingTreatment PeriodTreatment outcomeUltrasonic ImagingUltrasonogramUltrasonographyUltrasound DiagnosisUltrasound Medical ImagingUltrasound TestUnited StatesValidationclinical relevanceclinical testclinically relevantco-morbidco-morbiditycomorbiditydiagnostic ultrasoundhepatic neoplasiahepatic neoplasmhepatic tumorimagerimagingimaging platformimaging systemimprovedin vivokidney adenocarcinomaliver tumormalignancymillisecondmodel of animalmortalityneoplasm/cancerover-treatmentovertreatmentporcinepre-clinicalpreclinicalrenalresearch clinical testingresolutionssonogramsonographysound measurementsuidsurgerytranslational opportunitiestranslational potentialtreatment daystreatment durationtumortumor ablationultrasound imagingultrasound scanningurologicurologicalvalidations
Description preview
PROJECT SUMMARY: Renal cell carcinoma (RCC) is the sixth most common cancer in the United States, with
~ 82k new diagnoses estimated for 2023. Surgery is the preferred option for initial management of RCC, but the
number of patients who qualify is reduced each year due to the aging, comorbid population. Histotripsy is a
noninvasive, focused…
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