grant
Human Translational Bioinformatics Core
Organization UNIVERSITY OF CALIFORNIA LOS ANGELESLocation LOS ANGELES, UNITED STATESPosted 20 Sept 2018Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY2025Allelism TestBasic ResearchBasic ScienceBioinformaticsBioinformatics coreBioinformatics research coreBioinformatics resource coreBiologic ModelsBiologicalBiological MarkersBiological ModelsCandidate Disease GeneCandidate GeneCardiometabolic DiseaseCardiometabolic DisorderCell BodyCellsClinicalClinical ResearchClinical StudyCommunitiesComplementation TestComputer AnalysisComputer softwareCoronary ArteriosclerosisCoronary Artery DiseaseCoronary Artery DisorderCoronary AtherosclerosisDataData BasesData SetDatabasesDifferences between sexesDiffers between sexesDiseaseDisorderEnsureEpidemiologyGWA studyGWASGene ModifiedGenesGeneticGenetic Complementation TestGenetic studyGenomicsGenotypeGoalsHealthHospitalsHumanHuman ActivitiesHuman ResourcesIn VitroInbred Strains MiceIntuitionInvestigatorsKnowledgeLeadershipManpowerMiceMice MammalsModel SystemModern ManMolecularMultiomic DataMurineMusOn-Line SystemsOnline SystemsOutcomePathway interactionsPopulationProteomicsPublishingResearchResearch PersonnelResearch ResourcesResearchersResourcesRisk FactorsRoleSample SizeSeriesSex DifferencesSexual differencesSoftwareSystemSystems BiologyTrans TestTranslatingUpdateValidationVariantVariationVisualization softwareWomananalytical toolatherosclerotic coronary diseasebio-markersbiologicbiologic markerbiomarkerbiomarker identificationcandidate identificationcardiometaboliccardiometabolic riskcardiometabolismcohortcomplementation analysiscomplementation approachcomputational analysescomputational analysiscomputational infrastructurecomputer analysescomputer infrastructurecoronary arterial diseasecost effectivedata baseepidemiologicepidemiologicalexperienceexperimentexperimental researchexperimental studyexperimentsgene modificationgenetic associationgenetically modifiedgenome wide associationgenome wide association scangenome wide association studygenomewide association scangenomewide association studyhuman dataidentification of biomarkersidentification of new biomarkersin silicointernet resourceintuitivelarge scale datalarge scale data setslarge scale datasetsmarker identificationmenmetabolism measurementmetabolomicsmetabonomicsmouse modelmultiple data sourcesmultiple omic datamurine modelon-line compendiumon-line resourceonline compendiumonline computeronline resourceopen source toolopen source toolkitpathwaypersonnelphenomeprogramssearchable data basesearchable databasesex based differencessex dimorphismsex-dependent differencessex-related differencessex-specific differencessexual dimorphismsexually dimorphicsocial rolesuccesstargeted biomarkertooltraittranscriptomicsvalidationsvisualization toolweb basedweb based interfaceweb resourceweb-based resourcewhole genome association analysiswhole genome association study
Description preview
PROJECT SUMMARY
The overall objective of this SCORE is to elucidate sex differences in cardiometabolic disease and its risk
factors and treatments using genetically modified mouse models, inbred mouse strains, and in vitro or cell-based
experiments. However, another important component of the SCORE is to translate findings from model systems
to…
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