grant
Human Tissues, Lipidomics, and Proteomics Core
Organization NEW YORK UNIVERSITY D/B/A NYU LONG ISLAND SCHOOL OF MEDICINELocation MINEOLA, UNITED STATESPosted 1 May 2023Deadline 30 Apr 2028
NIHUS FederalResearch GrantFY2025ASCVDAdipocytesAdipose CellAdipose tissueApo-BApoBApolipoproteinsApolipoproteins BArterial Fatty StreakAssayAtherogenicityAtheromaAtheromatousAtheromatous degenerationAtheromatous plaqueAtherosclerosisAtherosclerotic Cardiovascular DiseaseBasic ResearchBasic ScienceBioassayBiogenesisBioinformaticsBiological AssayBiologyBlood PlasmaBody TissuesBody Weight decreasedCardiovascularCardiovascular Body SystemCardiovascular DiseasesCardiovascular Organ SystemCardiovascular systemCatabolismCentrifugationCentrifugation FractionationCeramidesClinicalCommunitiesDataData SetDiabetes MellitusFamilyFastingFat CellsFatty TissueGastrectomyGoalsHealthHeart VascularHumanHyperglyceridemiaHypertriglyceridemiaIndividualInstitutionIntermediary MetabolismInvestigatorsLaboratoriesLaser ElectromagneticLaser RadiationLasersLipidsLipocytesLipoproteinsLiverMacrophageMass Photometry/Spectrum AnalysisMass SpectrometryMass SpectroscopyMass SpectrumMass Spectrum AnalysesMass Spectrum AnalysisMature LipocyteMature fat cellMetabolic ProcessesMetabolismMethodsMiceMice MammalsModern ManMolecularMolecular Sieve ChromatographyMurineMusMφObesityOrigin of LifeOutcomePlasmaPlasma SerumProceduresProcessProtein FamilyProteinsProteomicsRaised TGRaised triglyceridesRegulationResearchResearch PersonnelResearchersReticuloendothelial System, Serum, PlasmaRiskRisk MarkerRisk ReductionRoleSamplingServicesSize Exclusion ChromatographyStandardizationSystems BiologyTechnologyTissuesTranslatingTriacylglycerolTriglyceridesUltracentrifugationWeight LossWeight Reductionadiposeadiposityanalytical methodanalytical toolatheromatosisatherosclerosis plaqueatherosclerotic diseaseatherosclerotic lesionsatherosclerotic plaqueatherosclerotic vascular diseasebio-informatics toolbioinformatics toolbody weight losscardiovascular disease riskcardiovascular disordercardiovascular disorder riskcirculatory systemclinical applicabilityclinical applicationclinical practiceclinical relevanceclinical riskclinically relevantcohortcorpulencecost effectivenessdiabeteselevated tgelevated triglycerideextracellular vesiclesfastedfastshepatic body systemhepatic organ systemhigh triglycerideshuman tissueincreased triglyceridesinstrumentationinterestlipidomicsmetabolism measurementmetabolomicsmetabonomicsmouse modelmurine modelnovelparticlephenotypic dataplaques in atherosclerosispre-clinicalpreclinicalreduce riskreduce risksreduce that riskreduce the riskreduce these risksreduces riskreduces the riskreducing riskreducing the riskrisk predictorrisk predictorsrisk-reducingsocial rolewhite adipose tissuewt-lossyellow adipose tissue
Description preview
SUMMARY – HUMAN TISSUES, LIPOPROTEINS, LIPIDOMICS, & PROTEOMICS CORE (C2)
The Human Tissues, Lipoproteins, Lipidomics, and Proteomics Core (Core 2, C2) will focus on
providing human tissues and analytical capabilities to all three projects to enhance translatability
of mouse studies proposed in P1–P3 to clinical practice in humans. In parallel,…
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