grant
Human Energy and Body Weight Regulation Core
Organization NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASESLocation UNITED STATES
NIHUS FederalResearch GrantFY20251,2-benzenediol1,2-dihydroxybenzene2-hydroxyphenol21+ years old3,4-Dihydroxyphenylacetic Acid3,4-dihydroxy-benzeneacetic acidAdultAdult HumanAirB blood cellsB cellB cellsB-CellsB-LymphocytesB-cellBackBiological MarkersBloodBlood PlasmaBlood Reticuloendothelial SystemBody CompositionBody TemperatureBody WeightBrain regionCalorimetryCancersCardiac ChronotropismCardiovascular DiseasesCatecholsChronicChronic DiseaseChronic Fatigue DisorderChronic Fatigue SyndromeChronic Fatigue and Immune Dysfunction SyndromeChronic IllnessChronic Infectious Mononucleosis-Like SyndromeClinicalClinical ProtocolsClinical ResearchClinical StudyCognitiveCollaborationsCommunicationDEXADOPACDXAData AnalysesData AnalysisDegenerative Neurologic DisordersDiabetes MellitusDietDietary InterventionDisablingDiseaseDisorderDopamineDorsumDouble-Blind MethodDouble-Blind StudyDouble-BlindedDouble-Masked MethodDouble-Masked StudyDual-Energy X-Ray AbsorptiometryDual-Energy Xray AbsorptiometryDysfunctionEEGElectroencephalogramElectroencephalographyEnergy ExpenditureEnergy MetabolismExercise TestExpression SignatureFatigueFunctional disorderFutureGene Expression ProfileGoalsGulf War IllnessGulf War SyndromeHeart RateHomeHomoprotocatechuic AcidHospitalsHumanHydroxytyramineImmuneImmunesInpatientsInterventionInvestigatorsKetonesKetosisL-DopaLack of EnergyLength of StayLevodopaMDS-UPDRSMDS-Unified Parkinson's Disease Rating ScaleME/CFSMalignant NeoplasmsMalignant TumorMeasurementMeasuresMedicalMedium chain triglyceridesMetabolicMetabolic PathwayMitochondriaModern ManModificationMotorMovement Disorder Society Unified Parkinson's Disease Rating ScaleMyalgic EncephalomyelitisNational Institutes of HealthNatureNervous System Degenerative DiseasesNeural Degenerative DiseasesNeural degenerative DisordersNeurodegenerative DiseasesNeurodegenerative DisordersNeurologic Degenerative ConditionsNeurologyNumber of Days in HospitalNutrition InterventionsNutritional InterventionsObesityObesity EpidemicOilsOut-patientsOutcomeOutpatientsOver weightOverweightPBMCParalysis AgitansParkinsonParkinson DiseaseParticipantPathway interactionsPatientsPeripheral Blood Mononuclear CellPersian Gulf SyndromePersonsPhenotypePhysical activityPhysiologyPhysiopathologyPlacebo ControlPlasmaPlasma SerumPopulationPostviral Fatigue SyndromePrimary ParkinsonismPublishingPyrocatecholsRandomizedRegulationResearchResearch ActivityResearch DesignResearch PersonnelResearchersRestReticuloendothelial System, Serum, PlasmaRoyal Free DiseaseSeveritiesStrategic PlanningStudy TypeSymptomsSystemTemperatureTimeUPDRSUnified Parkinson's Disease Rating ScaleUnited States National Institutes of HealthVeteransVisitabsorptionacceptability and feasibilityadiposityadulthoodanalytical methodbio-markersbiologic markerbiomarkercardiovascular disorderchronic disorderclinical phenotypecognitive assessmentcognitive testingcorpulencedata interpretationdegenerative diseases of motor and sensory neuronsdegenerative neurological diseasesdesigndesigningdiabetesdiet interventiondietsexperiencefitnessgene expression patterngene expression signaturehomeshospital dayshospital length of stayhospital stayinsightinstrumentketo dietketogenic dietmalignancymigrationmitochondrialneoplasm/cancerneurodegenerative illnessnon-motor symptomnonmotor symptomo-Dihydroxybenzenesobesity interventionobesity therapyobesity treatmentopen labelopen label studyortho-Dihydroxybenzenespathophysiologypathwaypatient populationphysical conditioningphysical healthplacebo controlledportabilitypreferenceprimary outcomerandomisationrandomizationrandomly assignedrecruitrespiratorysecondary outcomesexstudy designtranscriptional profiletranscriptional signaturetrendwillingness
Description preview
The Core continues to be a part of the Metabolic Clinical Research Unit (MCRU), which was established at NIH in 2007 under the first NIH Strategic Plan for Obesity Research (http://www.obesityresearch.nih.gov/strategic-plan). It is design to conduct research to identify potential causes and evaluate treatments of obesity. Currently 1/3 of the…
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