grant

Hox gene regulation of body size and asexual reproduction underlie regenerative abilities

Organization WEST VIRGINIA UNIVERSITYLocation MORGANTOWN, UNITED STATESPosted 11 Jul 2024Deadline 30 Apr 2029
NIHUS FederalResearch GrantFY2026AffectAnatomic SitesAnatomic structuresAnatomyAnimalsAsexual ReproductionBody SizeBody TissuesCell BodyCellsComplexDataDevelopmentDevelopmental GeneDissectionEvolutionFlatwormsFoundationsGene Action RegulationGene Expression RegulationGene RegulationGene Regulation ProcessGene TranscriptionGenesGenetic TranscriptionHOX geneHealthHomeo Box GenesHomeobox Family GeneHomeobox GenesHomeodoamin GeneHomeotic GenesHumanInvertebrataInvertebratesKnowledgeLinkModelingModern ManModificationMolecularMolecular AnalysisNatural regenerationOrganismPlanariansPlatyhelminthesPlatyhelminthsPlayProcessPropertyRNA ExpressionRNA interference screenRNAi screenRNAi-based screenRegenerationRegenerative MedicineRegenerative capacityRegulationResearchRoleTissuesTranscriptionVertebrate AnimalsVertebratesWorkdevelopmentalgene conservationgene functiongene regulatory networkimprovedinsightinterestliving systemnew approachesnovel approachesnovel strategiesnovel strategypermissivenessregenerateregenerate new tissueregenerate tissueregenerating damaged tissueregenerating tissueregeneration abilityregeneration capacityregenerativesocial roletissue regenerationtissue regrowthtissue renewaltissue specific regenerationvertebrata
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Abstract
The ability of certain animals to regenerate their cells and tissues has long been a subject of interest for

biologists due to its relevance to animal development and regenerative medicine. However, we still don't fully

understand why some animals regenerate so well, while others cannot. From a holistic perspective, the loss of…

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Hox gene regulation of body size and asexual reproduction underlie regenerative abilities — WEST VIRGINIA UNIVERSITY | U | Dev Procure