grant
Host genetic resistance to COVID-19
Organization DIVISION OF BASIC SCIENCES - NCILocation UNITED STATES
NIHUS FederalResearch GrantFY20252p23African American groupAfrican American individualAfrican American peopleAfrican American populationAfrican AmericansAge YearsAntibodiesBiologicalCD4 CellsCD4 Positive T LymphocytesCD4 T cellsCD4 helper T cellCD4 lymphocyteCD4+ T-LymphocyteCD4-Positive LymphocytesCD8CD8BCD8B1CD8B1 geneCOVID crisisCOVID disease severityCOVID epidemicCOVID pandemicCOVID severityCOVID-19COVID-19 crisisCOVID-19 disease severityCOVID-19 epidemicCOVID-19 eraCOVID-19 global health crisisCOVID-19 global pandemicCOVID-19 health crisisCOVID-19 infectionCOVID-19 pandemicCOVID-19 periodCOVID-19 public health crisisCOVID-19 severityCOVID-19 virus infectionCOVID-19 yearsCOVID19 disease severityCOVID19 infectionCOVID19 severityCV-19CollaborationsCoronavirus Infectious Disease 2019Data AnalysesData AnalysisDiseaseDisease OutcomeDisorderEthnic GroupEthnic PeopleEthnic PopulationEthnic individualEthnicity PeopleEthnicity PopulationGWA studyGWASGenesGeneticImmune Response GenesImmune responseIndividualInvestigatorsIr GeneLYT3Latin AmericanLytotoxicityMolecularResearch PersonnelResearchersSARS-CoV-2 disease severitySARS-CoV-2 epidemicSARS-CoV-2 global health crisisSARS-CoV-2 global pandemicSARS-CoV-2 infectionSARS-CoV-2 pandemicSARS-CoV-2 severitySARS-CoV2 infectionSARS-coronavirus-2 epidemicSARS-coronavirus-2 pandemicSamplingSevere Acute Respiratory Syndrome CoV 2 epidemicSevere Acute Respiratory Syndrome CoV 2 pandemicSevere acute respiratory syndrome coronavirus 2 epidemicSevere acute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 pandemicSeverity of illnessSiteT4 CellsT4 LymphocytesTestingVaccinationage stratificationbiologiccoronavirus disease 2019coronavirus disease 2019 crisiscoronavirus disease 2019 disease severitycoronavirus disease 2019 epidemiccoronavirus disease 2019 global health crisiscoronavirus disease 2019 global pandemiccoronavirus disease 2019 health crisiscoronavirus disease 2019 infectioncoronavirus disease 2019 pandemiccoronavirus disease 2019 public health crisiscoronavirus disease 2019 severitycoronavirus disease crisiscoronavirus disease epidemiccoronavirus disease pandemiccoronavirus disease severitycoronavirus disease-19coronavirus disease-19 global pandemiccoronavirus disease-19 pandemiccoronavirus infectious disease-19cytotoxicitydata interpretationdisease severityethnic subgroupethnicity groupgenetic associationgenetic resistancegenome wide associationgenome wide association scangenome wide association studygenomewide association scangenomewide association studyhost responseimmune system responseimmunoresponseinfected with COVID-19infected with COVID19infected with SARS-CoV-2infected with SARS-CoV2infected with coronavirus disease 2019infected with severe acute respiratory syndrome coronavirus 2responsesevere acute respiratory syndrome coronavirus 2 disease severitysevere acute respiratory syndrome coronavirus 2 global health crisissevere acute respiratory syndrome coronavirus 2 global pandemicsevere acute respiratory syndrome coronavirus 2 severitywhole genome association analysiswhole genome association study
Description preview
In collaboration with Dr. Stephen Chanock a multi-ancestry GWAS was performed on samples from the COVNET consortium which was rapidly created as the COVID-19 pandemic evolved. Samples were collected from 37 sites from around the world for this case-case GWAS of COVID-19 severity and allowed for the comparison of mild COVID-19 cases with…
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