Hijacking Hedgehog: identifying targetable pathways co-opted by Human Papillomavirus in cervical cancer
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Persistent HPV infection is the leading cause of cervical cancer. While the link between HPV infection and oncogenesis is very well-established, the mechanisms of HPV mediated transformation are not fully understood. STAT3 and GLI1 are potent oncogenes that have been associated with persistence of stem cells in many cancer types and were found to…
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