grant
High-Throughput Functional Genomics of Variants in Genes Linked to Substance Use Disorders
Organization WASHINGTON UNIVERSITYLocation SAINT LOUIS, UNITED STATESPosted 1 Aug 2023Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY2025AddressAgreementAssayBioassayBiologicalBiological AssayCodeCoding SystemCollaborationsDedicationsDevelopmentDiseaseDisorderDoctor of PhilosophyFellowshipFunctional RNAFundingFutureGWA studyGWASGene variantGenerationsGenesGeneticGenomic approachGrantHumanHuman GeneticsHuman GenomeInfrastructureInstitutionInvestigatorsInvestmentsLeadershipLinkMeasurementModern ManMolecularNational Institutes of HealthNeurodevelopmental DisorderNeurological Development DisorderNoncoding RNANontranslated RNANucleic Acid Regulator RegionsNucleic Acid Regulatory SequencesPathway interactionsPediatricsPh.D.PhDPhenotypePostdocPostdoctoral FellowProteinsQualifyingRegulatory RegionsReporterResearchResearch AssociateResearch PersonnelResearchersResidenciesSample SizeSubstance Use DisorderTalentsTechniquesTestingTherapeutic InterventionThinkingTrainingUnited States National Institutes of HealthUntranslated RNAVariantVariationWorkaddictionaddictive disorderallelic variantautistic childrenbiologiccareer developmentchildren on the autism spectrumchildren with ASDchildren with autismchildren with autism spectrum disorderclinical relevanceclinically relevantdevelop therapydevelopmentalexome sequencingexome-seqfunctional genomicsgenetic regulatory elementgenetic variantgenome sequencinggenome wide associationgenome wide association scangenome wide association studygenomewide association scangenomewide association studygenomic effortgenomic strategygenomic varianthuman whole genomeinnovateinnovationinnovativeinnovative technologiesintervention developmentintervention therapymodel organismmultidisciplinarymutation scanningmutation screeningneurodevelopmental diseaseneuropsychiatric diseaseneuropsychiatric disordernoncodingpathwaypost-docpost-doctoralpost-doctoral traineeprogramsrare mendelian conditionrare mendelian diseaserare mendelian disorderrational designresearch associatesscreeningscreeningssubstance usesubstance use and disordersubstance usingtherapy developmentthoughtstreatment developmentwhole genome association analysiswhole genome association study
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ABSTRACT
High-throughput functional genomics of variants in genes linked to substance use disorders
Understanding of the genetic basis of substance use disorders has advanced significantly in the recent past; the
generation of a reference human sequence in the early 2000’s enabled Genome Wide Association Studies
(GWAS), which in turn led to the…
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