grant
High-resolution functional imaging of speech-induced sensory modulation
Organization UNIVERSITY OF PITTSBURGH AT PITTSBURGHLocation PITTSBURGH, UNITED STATESPosted 18 Sept 2023Deadline 31 Jul 2028
NIHUS FederalResearch GrantFY202521+ years oldAccelerationAcousticsAdultAdult HumanAnatomic SitesAnatomic structuresAnatomyAreaAttenuatedAuditoryAuditory CortexAuditory areaBenchmarkingBest Practice AnalysisBiologic ModelsBiological ModelsBrainBrain MappingBrain Nervous SystemBrain regionCell Communication and SignalingCell NucleusCell SignalingCerebellar CortexCerebellumCodeCoding SystemComplexComputer ModelsComputerized ModelsDataDiagnosisDisfluentDysfluentEEGElectrocorticogramElectroencephalogramElectroencephalographyElectrophysiologyElectrophysiology (science)EncephalonEvoked PotentialsExperimental DesignsFeedbackFunctional ImagingFunctional MRIFunctional Magnetic Resonance ImagingFutureGRB-IRGRB10GRB10 geneGoalsHumanIndividualInfluentialsInterventionIntracellular Communication and SignalingInvestigationKnowledgeLearningLesionLinkLobuleMEG imagingMEG1MR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMagnetoencephalographyMapsMaternally Expressed Gene 1MeasurementMeasuresMediatingMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMethodsModel SystemModelingModern ManModernizationMonitorMotorMotor CortexMotor outputMovementNMR ImagingNMR TomographyNatureNeurobiologyNeurophysiology / ElectrophysiologyNuclear Magnetic Resonance ImagingNucleusOutputParticipantPathway interactionsPatternPersonalized medical approachPersonsPhoneticsPhysiologic ImagingPreparednessPrimatesPrimates MammalsProcessProductionReadinessResearchResolutionRoleSamplingSensorySeriesSignal TransductionSignal Transduction SystemsSignalingSpecificitySpeechSpeech DisordersSpeech ManifestationsStammeringStructure of superior temporal sulcusStutteringSuperior Temporal SulcusSuperior temporal gyrusSystemTechniquesTestingThalamic structureThalamusUncertaintyZeugmatographyadulthoodattenuateattenuatesauditory feedbackbenchmarkbiological signal transductionbody movementcerebellar lesioncomputational modelingcomputational modelscomputer based modelscomputer based predictioncomputerized modelingdesigndesigningdoubtelectrocorticographyelectrophysiologicalexperimentexperimental researchexperimental studyexperimentsfMRIgrowth factor receptor-bound protein 10improvedindividual heterogeneityindividual variabilityindividual variationindividualized approachinsightinterestlenslenseslocomotor learningmagnetoencephalogrammagnetoencephalographic imagingmotor controlmotor learningneuralneural imagingneuro-imagingneurobiologicalneuroimagingneurological imagingnon-speakingnon-verbalnon-vocalpathwaypersonalized approachphonologyphysiological imagingprecision approachpredictive modelingrecruitresolutionsresponsesensory cortexsensory feedbacksensory systemsocial rolesoundtailored approachthalamictheoriestool
Description preview
PROJECT SUMMARY / ABSTRACT
The overall goal of this project is to test and refine a neurobiological systems model of speech-induced sensory
modulation (SISM). Previous studies used magnetoencephalography (MEG) and electroencephalography (EEG)
to reveal that auditory cortical responses evoked when speaking are reduced compared to passive listening,…
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