grant
Harnessing machine learning to develop new antibiotics for Neisseria gonorrhoeae
Organization MASSACHUSETTS GENERAL HOSPITALLocation BOSTON, UNITED STATESPosted 12 Mar 2024Deadline 28 Feb 2029
NIHUS FederalResearch GrantFY202621+ years oldAIDS VirusAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAddressAdultAdult HumanAdvisory CommitteesAnimal ModelAnimal Models and Related StudiesAnti-Bacterial AgentsAntibiotic AgentsAntibiotic DrugsAntibiotic ResistanceAntibiotic TherapyAntibiotic TreatmentAntibioticsAntimicrobial ResistanceAwardAzadoseAzithromycinAzitrocinAzythromycinBacterial Drug ResistanceBiologicalBlindnessBody TissuesBypassCannot achieve a pregnancyCareer Development AwardsCareer Development Awards and ProgramsCareer Development Programs K-SeriesCefatriaxoneCeftriaxoneCell BodyCellsCessation of lifeChemical StructureChemicalsClinicalClinical PathologyClinical TrialsComputational toolkitConnectionist ModelsCutting edge antibioticsDataDeathDevelopmentDevelopment PlansDevelopment and ResearchDiagnosisDiagnosticDifficulty conceivingDoctor of PhilosophyDrug KineticsDrug Resistance in N. GonorrhoeaeDrug TherapyDrug resistanceDrug resistance in Neisseria GonorrhoeaeDrug resistant N. GonorrhoeaeDrug resistant bacteriumDrug-resistant N. GonorrhoeaeDrug-resistant Neisseria GonorrhoeaeDrugsEnvironmentFoundationsFrequenciesFutureGeneral HospitalsGeneralized GrowthGeneticGenomic approachGenomicsGoalsGonococcal InfectionGonococcusGonorrheaGram-Negative BacteriaGrowthHIVHealthHumanHuman Immunodeficiency VirusesIn VitroIn vivo analysisInfantInfectionInfertilityInvestigationInvestigatorsK-AwardsK-Series Research Career ProgramsKnowledgeLAV-HTLV-IIILearningLeftLibrariesLifeLymphadenopathy-Associated VirusMachine LearningMassachusettsMedicationMedicinal ChemistryMentorsMentorshipMicroscopicMiscellaneous AntibioticModelingModern ManMolecularMolecular TargetMulti-Drug ResistanceMultidrug ResistanceMultiple Drug ResistanceMultiple Drug ResistantN gonorrheaN. gonorrheaNeisseria gonorrhoeaeNeisseria gonorrhoeae antibiotic resistanceNeonatalNeural Network ModelsNeural Network SimulationOrganismPerceptronsPersonsPh.D.PhDPharmaceutic ChemistryPharmaceutical ChemistryPharmaceutical PreparationsPharmacokineticsPharmacological TreatmentPharmacotherapyPhenotypePhysiciansPostdocPostdoctoral FellowPredispositionPregnancy ComplicationsPrevalencePropertyProteomicsPublic HealthR & DR&DReportingResearchResearch AssociateResearch Career ProgramResearch PersonnelResearch ResourcesResearchersResistanceResistance developmentResistance to Multi-drugResistance to MultidrugResistance to Multiple DrugResistance to antibioticsResistant developmentResistant to Multiple DrugResistant to antibioticsResistant to multi-drugResistant to multidrugResourcesRiskScientistSeriesSexual TransmissionStructureSusceptibilityTask ForcesTestingTherapeutic InterventionTissue GrowthTissuesToxic effectToxicitiesTrainingTreatment FailureUltreonVirus-HIVWorkZithromaxZitromaxadulthoodadvisory teamanti-bacterialanti-bacterial drug resistanceanti-bacterial drug resistantanti-bacterial resistanceanti-bacterial resistantanti-microbialanti-microbial resistantantibiotic drug resistanceantibiotic resistantantibiotic resistant N. gonorrhoeaeantibiotic resistant Neisseria gonorrhoeaeantibiotic-resistant N. gonorrhoeaeantimicrobialbacterial disease treatmentbacterial infectious disease treatmentbiologiccareer developmentcellular targetingchemical librarycomplications during pregnancycomputational toolboxcomputational toolscomputational toolsetcomputerized toolsdata to traindataset to traindesigndesigningdeveloping resistancedevelopmentaldrug developmentdrug discoverydrug interventiondrug resistantdrug resistant bacteriadrug treatmentdrug-like chemicaldrug-like compounddrug-like moleculedrug/agentexperienceexperimentexperimental researchexperimental studyexperimentsfertility cessationfertility lossfuture antibioticsgenomic effortgenomic strategygonococcal antibiotic resistancegraph attention networkgraph convolutional networkgraph neural networkimprovedin silicoin vivoin vivo evaluationin vivo testingindexinginfected vaginallyinfertileinnovateinnovationinnovativeinsightintervention therapyliving systemmachine based learningmachine learning based modelmachine learning based prediction modelmachine learning based predictive modelmachine learning modelmachine learning predictionmachine learning prediction modelmodel of animalmouse modelmulti-drug resistantmultidrug resistantmurine modelnew approachesnew generation antibioticsnext generation antibioticsnextgen antibioticnovelnovel approachesnovel strategiesnovel strategyontogenypharmaceutical interventionpharmacological interventionpharmacological therapypharmacology interventionpharmacology treatmentpharmacotherapeuticspost-docpost-doctoralpost-doctoral traineepre-clinicalpreclinicalpredictive toxicologypregnancy-related complicationsresearch and developmentresearch associatesresistance mechanismresistance to Drugresistance to anti-bacterialresistance to anti-microbialresistantresistant mechanismresistant to Drugresistant to anti-bacterialresistant to antimicrobialscreeningscreeningssexually transmittedskillssmall molecule librariestherapy failuretoxicity predictiontraining datatraining datasetsurgent antibiotic resistanceurgent antibiotic resistantvaginal biomevaginal infectionvaginal microbiomevirtualvirtual screeningvirtual screeningsvision lossvisual loss
Description preview
PROJECT SUMMARY/ABSTRACT
This proposal presents a five-year research and career development plan focused on machine learning
(ML)-guided antibiotic development for multidrug-resistant Neisseria gonorrhoeae. The candidate, Melis
Anahtar, MD, PhD, has completed clinical pathology training at Massachusetts General Hospital (MGH) and is
now a…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click