grant

Harmonized Healing: Personalized Music Interventions to Address Chronic Pain in People Living with HIV

Organization BRIGHAM AND WOMEN'S HOSPITALLocation BOSTON, UNITED STATESPosted 8 Sept 2025Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY2025AIDS VirusAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAddressAdherenceAdjuvantAffectAgingAnalgesic AgentsAnalgesic DrugsAnalgesic PreparationAnalgesicsAnodynesAntidotesAntinociceptive AgentsAntinociceptive DrugsAnxietyBehavior Conditioning TherapyBehavior ModificationBehavior TherapyBehavior TreatmentBehavioralBehavioral Conditioning TherapyBehavioral ModificationBehavioral SciencesBehavioral TherapyBehavioral TreatmentBiologic FactorBiologicalBiological FactorsCaringCausalityCell PhoneCellular PhoneCellular TelephoneCharacteristicsChronicChronic DiseaseChronic IllnessClinical ManagementClinical TrialsCommunitiesCommunity Health CentersConditioning TherapyCustomDataDevelopmentDrug TherapyEnrollmentEnsureEpidemicEtiologyFeedbackGoalsHIVHealthHealth PsychologyHealth behaviorHuman Immunodeficiency VirusesImpairmentIndividualInflammationInterventionInterviewLAV-HTLV-IIILow-resource areaLow-resource communityLow-resource environmentLow-resource regionLow-resource settingLymphadenopathy-Associated VirusManualsMeasuresMediatorMental HealthMental HygieneMental disordersMental health disordersMethodologyMethodsMobile PhonesModelingMoodsMorbidityMorbidity - disease rateMusicMusic InterventionMusic TherapyNCCAMNCCIHNational Center for Complementary and Integrative HealthNational Center for Complementary and Integrative MedicineNational Institutes of HealthNeighborhood Health CenterNeurosciencesPainPain ControlPain TherapyPain ThresholdPain Tolerance LevelPain managementPainfulParticipantPathway interactionsPersonsPharmacological TreatmentPharmacotherapyPositionPositioning AttributePreparationProtocolProtocols documentationPsychiatric DiseasePsychiatric DisorderPsychological HealthPsychosocial FactorPsychosocial StressPsychotherapyRandomized, Controlled TrialsReportingReproducibilityResource-constrained areaResource-constrained communityResource-constrained environmentResource-constrained regionResource-constrained settingResource-limited areaResource-limited communityResource-limited environmentResource-limited regionResource-limited settingResource-poor areaResource-poor communityResource-poor environmentResource-poor regionResource-poor settingRiskServicesSeveritiesSiteStandardizationStreamStructureTestingTheriacsUnited States National Institutes of HealthUrban CommunityVirus-HIVWorkacceptability and feasibilityantiretroviral therapyantiretroviral treatmentapp based deliveryapp deliveryapp-deliveredbehavior interventionbehavioral interventionbiobehaviorbiobehavioralbiologicbiopsychosocialcare as usualcare seekingcausationchronic disorderchronic painchronic pain controlchronic pain interventionchronic pain managementchronic pain patientchronic pain therapychronic pain treatmentco-morbidco-morbiditycohortcomorbiditycustomsdesigndesigningdevelopmentaldisease causationdisparity in healthdrug interventiondrug treatmentenrollexperiencefeasibility testingfeasibility trialhealinghealth disparityhealth related behaviorhealthy volunteeriPhoneimprovedinflammatory paininnovateinnovationinnovativeinsightmental illnessmind/bodymobile application deliveredmobile application deliverymortalitymulti-site trialmultidisciplinarymultisite trialnegative affectnegative affectivityneuralneuropathic painnon-medical opioid usenonmedical opioid useopiate misuseopioid misusepain interventionpain killerpain medicationpain modelpain reductionpain relieverpain tolerancepain treatmentpainful neuropathypainkillerpathwaypatient with chronic painpersonalized health interventionpersonalized interventionpharmaceutical interventionpharmacological interventionpharmacological therapypharmacology interventionpharmacology treatmentpharmacotherapeuticsprecision interventionspreparationspreventpreventingprimary outcomepsychiatric illnesspsychoeducationpsychologicpsychologicalpsychological disorderpsychological symptompsychosocial variablesrandomized control trialrecruitreduce painresponsesmart phonesmartphonesubstance misusesubstance usesubstance usingtherapy adherencetherapy compliancetreat chronic paintreatment as usualuser centered designusual carewhole healthwhole person health
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PROJECT SUMMARY: With increasingly efficacious strategies to treat HIV, the paradigm continues to shift to conceptualize HIV as a chronic disease. This has resulted in people with HIV (PWH) aging and developing chronic disease. Among HIV comorbidities, chronic pain is common and undertreated. This is a significant problem because untreated,…

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