grant
Hair Bundle Proteins
Organization OREGON HEALTH & SCIENCE UNIVERSITYLocation PORTLAND, UNITED STATESPosted 1 Jul 1994Deadline 30 Jun 2029
NIHUS FederalResearch GrantFY2025AbbreviationsActinsAddressAffectAgeApicalAuditoryC57BL/6 MouseCDH23CDH23 geneCDHR23Cadherin-23Cadherin-Related Family, Member 23CadherinsCalibrationCategoriesCell BodyCell Communication and SignalingCell SignalingCellsCellular MatrixCellular MechanotransductionChickCochleaCochlear OrganComplementComplement ProteinsComplexCorti CellCoupledCytoskeletal SystemCytoskeletonDNA mutationDataData SetDefectDevelopmentDimensionsElectron MicroscopyEmbryoEmbryo DevelopmentEmbryogenesisEmbryonicEmbryonic DevelopmentFilamentFreeze SubstitutionFreezingGeneralized GrowthGenesGenetic ChangeGenetic defectGenetic mutationGoalsGrowthHLA-DR Associated Protein IIHairHair CellsHealthHearing DisordersHearing LossHearing problemHeightHypoacusesHypoacusisIGAADIlluminationImageIndividualInhibitor of GZMA-Activated DNaseInner Hair CellsInner ear hair cellsIntracellular Communication and SignalingKinociliumKnock-outKnockoutLaboratoriesLengthLightingLinkLocationMYO7AMYO7A geneMYO7A gene productMeasurementMeasuresMechanical Signal TransductionMechanicsMechanosensory TransductionMediatingMiceMice MammalsMicroscopyModelingMolecular MotorsMotorMouse ProteinMurineMusMutant Strains MiceMutationOtocadherinOuter Hair CellsPCDH15PCDH15 genePathway interactionsPatternPersonsPhasePhosphatase 2A Inhibitor I2PP2APolymersPositionPositioning AttributePreparationProcessProteinsPublishingQOLQuality of lifeRegulationRoleSET Translocation Inhibitor-2 of Protein Phosphatase-2ASamplingScanning Electron MicroscopySchemeSensory HairSet proteinShapesSignal TransductionSignal Transduction SystemsSignalingStructureSurfaceSyndromeTemplate Activating Factor I BetaTherapeuticTissue GrowthTransmission Electron MicroscopyVestibular DiseasesVestibular System ImpairmentVestibular defectVestibular disorderVestibular dysfunctionVestibular problemsVestibular system disorderVestibulopathyVisualizationWidthWorkagesauditory diseaseauditory disorderauditory dysfunctionauditory problembalance disorderbalance impairmentbasebasesbiological signal transductioncartilage link proteincell typecomplementationconditional knock-outconditional knockoutdeafnessdepolymerizationdevelopmentaldisturbed balancedysfunctional hearingear hair cellequilibration disorderequilibrium disorderexperimentexperimental researchexperimental studyexperimentsgenetic approachgenetic hearing impairmentgenetic hearing lossgenetic strategygenome mutationhair cell regenerationhearing challengedhearing defecthearing deficienthearing deficithearing difficultyhearing diseasehearing dysfunctionhearing impairmenthearing restorationhereditary hearing impairmenthereditary hearing lossimaginginherited hearing impairmentinherited hearing lossinterestintracellular skeletonlink proteinmechanicmechanicalmechanosensingmechanotransductionmouse geneticsmouse mutantmyosin VIIaontogenypathwaypolymerpolymericpolymerizationpost-natal developmentpostnatalpostnatal developmentpreparationspressureprotocadherin 15protocadherin-related 15public health relevancerestore hearingsocial rolesoundsuccesssuperresolution imagingvestibular deficitvestibular impairmentvestibular system dysfunctionvibration
Description preview
Project Summary
This project’s long-term objective is to elucidate mechanisms that control hair-bundle development and function,
show how defects in these mechanisms cause deafness and vestibular disorders, and identify pathways that
could be modulate to ameliorate these syndromes. Because the ability to control bundle development may assist
in…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click