Good Vibrations: Using Raman Spectroscopy and Molecular Dynamics to Shed Light on the Aggregation Mechanism of Tau in Alzheimer's Disease
Description preview
Alzheimer's disease (AD) is a neurodegenerative disorder that affects 36 million people worldwide.
Owing to an increased life expectancy and aging populations, by 2050 more 115 million are predicted to have AD. The pathology of AD results from the progressive accumulation of protein aggregates (called amyloid plaques and neurofibrillary tangles)…
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