grant
Glial ion channels in glia/neurons interactions
Organization UNIVERSITY OF MIAMI SCHOOL OF MEDICINELocation CORAL GABLES, UNITED STATESPosted 1 Jun 2018Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY20253'5'-cyclic ester of AMP3,5 cyclic AMP synthetase4-Aminobutanoic Acid4-Aminobutyric Acid4-amino-butanoic acid5-HT5-HT Receptors5-Hydroxytryptamine5-Hydroxytryptamine Receptors5HTAdenosine Cyclic 3',5'-MonophosphateAdenosine Cyclic MonophosphateAdenosine, cyclic 3',5'-(hydrogen phosphate)Adenyl CyclaseAdenylate CyclaseAdenylyl CyclaseAminalonAminaloneAntigen-Presenting CellsAreaBasic ResearchBasic ScienceBehaviorBehavioral AssayBrainBrain Nervous SystemC elegansC. elegansC.elegansCaenorhabditis elegansCalciumCaringCell BodyCell Communication and SignalingCell SignalingCellsCommunicationComplexCorpusculum TactusCyclic AMPDataDedicationsDiseaseDisorderENaCEncephalonEndowmentEnteramineEnvironmentEpithelial CellsExclusionFeedbackFunctional ImagingFundingGABAGenesGeneticGliaGlial CellsGoalsHarvestHippophaineHumanImageImaging DeviceImaging InstrumentImaging ToolInjuryIntracellular Communication and SignalingIon ChannelIonic ChannelsKnock-outKnockoutKolliker's reticulumMammaliaMammalsMediatingMeissners CorpuscleMembrane ChannelsMerkel CellsMerkel's ReceptorModelingModern ManMolecularNasalNasal Passages NoseNerveNerve CellsNerve EndingsNerve Impulse TransmissionNerve TransmissionNerve Transmitter SubstancesNerve UnitNervous SystemNeural CellNeurocyteNeurogliaNeuroglial CellsNeurologic Body SystemNeurologic Organ SystemNeuromodulatorNeuronal TransmissionNeuronsNeuropeptidesNeurotransmittersNon-neuronal cellNonneuronal cellNoseOrganOrganismOutputOval CorpusclePerceptionPhysiologic ImagingPhysiologyPlayProcessPublishingRNA SeqRNA sequencingRNAseqReceptor ProteinRegulationRespiratory System, Nose, Nasal PassagesRoleSensorySerotoninSignal TransductionSignal Transduction SystemsSignalingSkinSystemTactile CorpuscleTestingTouchTouch CorpuscleTouch sensationTransducersTraumaVertebrate AnimalsVertebratesWorkaccessory celladenosine 3'5' monophosphateaxon signalingaxon-glial signalingaxonal signalingbiological signal transductioncAMPcell typeepithelial Na+ channelepithelial sodium channelexcitatory neuronexperimentexperimental researchexperimental studyexperimentsgamma-Aminobutyric Acidglia signalingglial activationglial cell activationglial signalingimagingin vivoinjuriesknock-downknockdownliving systemmechanical forcemodel organismmutantnerve cementnerve signalingneural signalingneuronalneuronal excitabilityneuronal signalingneurotransmissionnoveloffspringoptogeneticsphysiological imagingreceptorrepairrepairedresponsesensory systemserotonin receptorsocial attachmentsocial bondingsocial roletactile sensationtooltranscriptome sequencingtranscriptomic sequencingvertebrataγ-Aminobutyric Acid
Description preview
PROJECT SUMMARY
Touch is essential for our survival and for social bonding, and in disrupted in many forms of injuries and
disease states. Despite its fundamental importance, touch transduction remains one of the least understood
signaling processes, both at the cellular and molecular levels. Touch is mediated by receptors imbedded in the
skin,…
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