grant

Genetically Engineered Mouse Models (GEMM)

Organization ST. JUDE CHILDREN'S RESEARCH HOSPITALLocation MEMPHIS, UNITED STATESPosted 1 Apr 1997Deadline 31 Mar 2031
NIHUS FederalResearch GrantFY2026AllelesAllelomorphsAnimal ModelAnimal Models and Related StudiesAnimalsBirth RateBloodBlood Reticuloendothelial SystemCCSGCRISPRCRISPR approachCRISPR based approachCRISPR methodCRISPR methodologyCRISPR techniqueCRISPR technologyCRISPR toolsCRISPR-CAS-9CRISPR-based methodCRISPR-based techniqueCRISPR-based technologyCRISPR-based toolCRISPR/CAS approachCRISPR/Cas methodCRISPR/Cas systemCRISPR/Cas technologyCRISPR/Cas9CRISPR/Cas9 technologyCancer Center Support GrantCas nuclease technologyCell BodyCellsClustered Regularly Interspaced Short Palindromic RepeatsClustered Regularly Interspaced Short Palindromic Repeats approachClustered Regularly Interspaced Short Palindromic Repeats methodClustered Regularly Interspaced Short Palindromic Repeats methodologyClustered Regularly Interspaced Short Palindromic Repeats techniqueClustered Regularly Interspaced Short Palindromic Repeats technologyCollaborationsComprehensive Cancer CenterConsultationsCustomDNA mutationDoctor of PhilosophyEconomicsEducation and TrainingElectroporationEnsureEquipmentFertilized EggFertilized OvumFundingGEM modelGEMM modelGenerationsGenesGenetic ChangeGenetic defectGenetic mutationGenetically Engineered MouseGenome engineeringGenotypeIndustryInjectionsInvestigatorsJournalsKI miceKnock-in MouseKnock-outKnockoutLearningLive BirthMagazineMalignant CellMethodsMiceMice MammalsModelingMouse ES CellMouse ESCMouse Embryonic ProgenitorMouse Embryonic Stem CellsMurineMusMutationNatureOncogenesisPh.D.PhDPhasePhenotypePoint MutationProductionPublicationsQualifyingReagentReportingResearchResearch PersonnelResearchersResource SharingRoleSaint JudeSaint Jude Children's Cancer CenterSaint Jude Children's Research HospitalScienceScientific PublicationServicesSt. JudeSt. Jude Children's Cancer CenterSt. Jude Children's Research HospitalSt. Jude Children's Research Hospital Comprehensive Cancer CenterSt.Jude Children's Cancer CenterSt.Jude Children's Research HospitalSt.Jude Children's Research Hospital Comprehensive Cancer CenterTechnical ExpertiseTechniquesTechnologyTimeTrainingTraining and EducationTransgenic MiceTransgenic OrganismsUniversitiesVendoranti-cancer treatmentarmcancer cellcancer progressionconditional knock-outconditional knockoutconsultationcostcost effectivecustomsdesigndesigningeconomicelectroporative deliveryexperiencegene editing methodgene editing methodologygene editing strategygene editing techniquesgene electrotransfergene-editing approachgenetic approachgenetic strategygenetically engineered mouse modelgenetically engineered murine modelgenome editinggenome mutationgenomic editinggraduate studentknockin miceknockout genelecturesmESCmembermodel designmodel of animalmouse geneticsmouse modelmurine ES cellsmurine ESCmurine embryonic progenitormurine embryonic stem cellmurine modelneoplasm progressionneoplastic progressionprogramsresponsesocial rolesq. ftsquare foottechnical skillstherapeutic targettooltransgenictumor progressiontumorigenesiszygote
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PROJECT SUMMARY/ABSTRACT – GENETICALLY ENGINEERED MOUSE MODELS SHARED
RESOURCE

The Genetically Engineered Mouse Models Shared Resource (GEMMSR), formerly the Transgenic Gene

Knockout Shared Resource, provides St. Jude Comprehensive Cancer Center (SJCCC) members with

convenient and economic access to generating genetically engineered mouse models…

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Genetically Engineered Mouse Models (GEMM) — ST. JUDE CHILDREN'S RESEARCH HOSPITAL | UNITED STATES | Apr 1997 | Dev Procure