grant
Genetic variation underlying innate lymphoid cell phenotypes across hosts
Organization STANFORD UNIVERSITYLocation STANFORD, UNITED STATESPosted 5 Sept 2025Deadline 4 Sept 2029
NIHUS FederalResearch GrantFY2025Adoptive TransferAffectAmericanAutoregulationBacterial InfectionsBasal Transcription FactorBasal transcription factor genesBiologyBody TissuesC57BL/6 MouseCCR6CCR6 geneCKRL3Cell BodyCell Communication and SignalingCell MaturationCell SignalingCellsCellular Immune FunctionChIP SequencingChIP-seqChIPseqChemokine Receptor GeneChemokine Receptor-Like 3ChromatinDNA BindingDNA Binding InteractionDNA boundDNA mutationDataDevelopmentEnhancersEnteralEntericEpithelial CellsEpitheliumExhibitsG Protein-Coupled Receptor 29GPR29GPRCY4Gastrointestinal DiseasesGastrointestinal PhysiologyGeneral Transcription Factor GeneGeneral Transcription FactorsGeneticGenetic ChangeGenetic DiversityGenetic PolymorphismGenetic VariationGenetic defectGenetic mutationGenomicsGoalsGut EpitheliumHomeostasisHost Defense MechanismIgAImmuneImmunesImmunityImmunoglobulin AInbreedingInflammationInflammatory Bowel DiseasesInflammatory Bowel DisorderIntestinalIntestinesIntracellular Communication and SignalingKnowledgeLaboratory miceLineage TracingLymphocyte SubtypingsLymphoid CellMaintenanceMediatingMiceMice MammalsMouse StrainsMucosaMucosal TissueMucous MembraneMurineMusMutationNucleic Acid Regulator RegionsNucleic Acid Regulatory SequencesPathway interactionsPatternPhenotypePhysiologicPhysiologicalPhysiological HomeostasisPopulationPositionPositioning AttributePreventative measurePreventive measureProductionProteinsRegulationRegulatory RegionsRegulatory T-LymphocyteResearchRoleSTRL22ShapesSignal TransductionSignal Transduction SystemsSignalingTestingTissuesTranscription Factor Proto-OncogeneTranscription factor genesTregWorkbacteria infectionbacterial diseasebiological signal transductionbowelcell lineage analysiscell lineage mappingcell lineage tracingcell lineage trackingcellular lineage mappingcellular lineage trackingchemokine receptorchromatin immunoprecipitation coupled with sequencingchromatin immunoprecipitation followed by sequencingchromatin immunoprecipitation with sequencingchromatin immunoprecipitation-seqchromatin immunoprecipitation-sequencingcolorectal cancer riskcytokinedevelopmentalfitnessgastrointestinal disordergastrointestinal epitheliumgenetic regulatory elementgenome mutationimmune functionin vitro Assayin vivoinflammatory disease of the intestineinflammatory disorder of the intestineinsightintestinal autoinflammationintestinal barrierintestinal epitheliumintestinal mucosal barriermicroorganismnovelpathwaypolymorphismprogenitorreceptor expressionrecruitregulatory T-cellsresponsesocial roletraittranscription factor
Description preview
Project Summary
Maintenance of gut epithelial homeostasis requires signals from a specialized set of RORγt+
innate lymphoid cells (ILCs) that reside in mucosa. RORγt+ ILCs directly regulate the gut
barrier by secreting cytokines that activate epithelial host defense mechanisms and reinforce
gut barrier integrity. Among the RORγt+ ILCs, there…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click