grant
Functional Magnetic Resonance Imaging and Deep Learning to Improve Deep Brain Stimulation Therapy
Organization GE MEDICAL SYSTEMS INFORMATION TECHNOLOGIES, INCLocation NISKAYUNA, UNITED STATESPosted 19 Sept 2023Deadline 30 Nov 2028
NIHUS FederalResearch GrantFY2026AD dementiaAI systemAdoptionAdverse effectsAlzheimer Type DementiaAlzheimer disease dementiaAlzheimer sclerosisAlzheimer syndromeAlzheimer'sAlzheimer's DiseaseAlzheimers DementiaArtificial IntelligenceBenign Essential TremorBilateralBody TissuesBrainBrain Nervous SystemCell Communication and SignalingCell SignalingClassificationClinicalComplicationComputer ReasoningConsumptionData CollectionDeep Brain StimulationDystoniaElectrodesEncephalonEngineeringEnsureEssential TremorFinancial HardshipFrequenciesFunctional MRIFunctional Magnetic Resonance ImagingGoalsHealthHourImplantImplanted ElectrodesImprove AccessIntracellular Communication and SignalingLocationMR ImagingMR TomographyMRIMRIsMachine IntelligenceMagnetic Resonance ImagingMajor Depressive DisorderManualsMapsMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMethodsModelingMuscle DystoniaNMR ImagingNMR TomographyNeurologistNeurosurgeonNuclear Magnetic Resonance ImagingOperative ProceduresOperative Surgical ProceduresOutcomeParalysis AgitansParkinsonParkinson DiseasePathologicPatient outcomePatient-Centered OutcomesPatient-Focused OutcomesPatientsPhysiciansPhysiologic pulsePilot ProjectsPrimary ParkinsonismPrimary Senile Degenerative DementiaProtocolProtocols documentationPublishingPulseQOL improvementQualifyingReportingResearchSTN stimulationSamplingSignal TransductionSignal Transduction SystemsSignalingSurgicalSurgical InterventionsSurgical ProcedureSystemSystematicsTestingTherapeuticTimeTissuesUniversitiesVisitWidthZeugmatographybiological signal transductionbrain volumeclinical careclinical depressionclinical validationcomparable efficacycomparative efficacycompare efficacycomputer based predictiondata acquisitiondata acquisitionsdata to traindataset to traindeep learningdeep learning based modeldeep learning methoddeep learning modeldeep learning strategyeconomic hardshipeconomic strainenergy efficiencyfMRIfeature extractionfinancial adversityfinancial burdenfinancial distressfinancial insecurityfinancial instabilityfinancial strainfinancial stressfinancial worryimprovedimprovements in QOLimprovements in quality of lifeinterestmajor depressionmajor depression disordermild cognitive declinemild cognitive disordermild cognitive dysfunctionmild cognitive impairmentmild cognitive lossmild neurocognitive impairmentmultidisciplinaryneuro-surgeonnovelpatient oriented outcomespilot studypredictive modelingprimary degenerative dementiaprogramsquality of life improvementradiologistrapid methodrapid techniqueresponsesenile dementia of the Alzheimer typeside effectstandard of caresubthalamic nucleus stimulationsuccesssurgerytraining datatraining datasetstreatment centervalidation studiesvoltage
Description preview
PROJECT SUMMARY/ABSTRACT
Successful treatment of Parkinson's disease (PD) using deep brain stimulation (DBS) therapy requires an
optimal setting of stimulation parameters to correct brain function anomalies. The commonly employed DBS
1.0 electrodes have only four contact locations (with no stimulation directionality) that are used to electric…
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