grant
Frontal Striatal Systems and Dopamine in Normal and Pathological Behavior
Organization NATIONAL INSTITUTE OF MENTAL HEALTHLocation UNITED STATES
NIHUS FederalResearch GrantFY202512-20 years oldAdolescenceAmygdalaAmygdaloid BodyAmygdaloid NucleusAmygdaloid structureAnimal ModelAnimal Models and Related StudiesAnimalsAnxietyAnxiety DisordersAreaBasal GangliaBasal NucleiBehaviorBehavioralBrainBrain Nervous SystemCell Communication and SignalingCell SignalingClinicalCodeCoding SystemCognitionComputer ModelsComputerized ModelsConceptionsCorpus StriatumCorpus striatum structureDA NeuronDevelopmentDiseaseDisorderDopamineDopamine neuronDorsalEmotionalEncephalonEventFeelingFoodGlobus PallidusGoalsHumanHydroxytyramineImageIntracellular Communication and SignalingLeadLearningLifeLimbic SystemLiquid substanceMental DepressionMental disordersMental health disordersModelingModern ManOutcomePathologicPathologyPatientsPb elementPharmacologyPhylogenetic AnalysisPhylogeneticsPlayPopulationPrefrontal CortexPrevalencePrimatesPrimates MammalsProcessPsychiatric DiseasePsychiatric DisorderPublic HealthPunishmentResearchRewardsRoleSignal TransductionSignal Transduction SystemsSignalingSocial Support SystemSocietiesStriate BodyStriatumStructureStudentsSupport SystemSystemThalamic structureThalamusTraumaVentral StriatumVertebrate AnimalsVertebratesWorkaddictionaddictive disorderadolescence (12-20)amygdaloid nuclear complexbasebasesbiological signal transductioncomputational modelingcomputational modelscomputer based modelscomputerized modelingcostdepressiondevelopmentaldopamine systemdopaminergic neuronexperienceexperimentexperimental researchexperimental studyexperimentsfeelingsfluidheavy metal Pbheavy metal leadimagingliquidmental illnessmodel of animalmotivational processesneuralneurophysiologicalneurophysiologypallidumprogramspsychiatric illnesspsychological disorderreinforcersocial rolestriatalteacherthalamicvertebrata
Description preview
Our lab uses a combination of computational modeling, neurophysiology, pharmacology and imaging to understand how a set of brain areas composed of the amygdala, striatum, pallidum, thalamus, prefrontal cortex and dopamine underlie learning from emotional events. These areas are connected in highly organized networks, and we base our studies on…
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