grant

Flicker photophobia as an experience of inefficient coding

Organization UNIVERSITY OF PENNSYLVANIALocation PHILADELPHIA, UNITED STATESPosted 1 Jun 2024Deadline 31 Mar 2028
NIHUS FederalResearch GrantFY2025BrainBrain Nervous SystemCephalalgiaCephalgiaCephalodyniaCodeCoding SystemCognitive DiscriminationCranial PainDataDetectionDevelopmentDevicesDiffuseDisablingDiscriminationEncephalonEnvironmentEnvironmental ExposureExperimental PsychologyExposure toEyeglassesFrequenciesFunctional MRIFunctional Magnetic Resonance ImagingHead PainHeadacheHumanHypersensitivityImageInformation StorageJudgmentLightLight SensitivityLinkMeasurementMeasuresMigraineMigraine HeadacheModelingModern ManNervous System DiseasesNervous System DisorderNeurologic DisordersNeurological DisordersParticipantPerceptionPersonsPhotophobiaPhotoradiationPhysical activityPlayPredispositionPropertyPsychophysicsPublicationsResearchResearch ResourcesResourcesRoleScientific PublicationSensorySpectaclesStimulusStructureSusceptibilitySymptomsTestingTimeUncertaintyVariantVariationVisualVisual CortexVisual DiscomfortVisual SystemVisual disabilityVisually disabledWorkbehavior measurementbehavioral measurebehavioral measurementdevelopmentaldisability burdendoubtexpectationexperiencefMRIfunction luminancehead achehuman modelimaginginformation processingluminancemanage symptommodel of humanneuralneurological diseaseneuropsychiatric diseaseneuropsychiatric disordernovelperceptual stimulusphysicochemical phenomena related to the sensespsychophysicalresponsesensory stimulussocial rolestatisticssymptom managementusabilityvision disabilityvisual corticalvisual stimuluswearablewearable devicewearable electronicswearable systemwearable technologywearable toolwearables
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Project Summary
A canonical feature of migraine is visual discomfort (i.e., “photophobia”), with particular sensitivity to flicker

(time-varying modulations of light). We lack a mechanistic understanding of this symptom generally, and

specifically require a framework that unites the phenomenon of discomfort with the properties of the visual…

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Flicker photophobia as an experience of inefficient coding — UNIVERSITY OF PENNSYLVANIA | UNITED STATES | Jun 2024 | Dev Procure