grant

Exploiting metabolite GPCR mechanotransduction to find new treatments for metabolic disorders

Organization UKRILocation United Kingdom
UKRIUK ResearchGrantActive
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Description preview

GPCRs are the largest family of membrane proteins and most successful drug targets. Recently a group of metabolite sensing GPCRs has attracted interest in the treatment of metabolic disorders, including obesity and diabetes. In these disorders significant remodeling of adipose tissue occurs, leading to changes in the mechanical properties of the…

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Exploiting metabolite GPCR mechanotransduction to find new treatments for metabolic disorders — UKRI | United Kingdom | Dev Procure