grant
Epigenetic regulation of stress-potentiated ethanol drinking
Organization LOUISIANA STATE UNIV A&M COL BATON ROUGELocation BATON ROUGE, UNITED STATESPosted 15 Aug 2025Deadline 30 Apr 2030
NIHUS FederalResearch GrantFY20263-D Imaging3D imagingAlcohol Chemical ClassAlcohol DrinkingAlcohol consumptionAlcoholsAmygdalaAmygdaloid BodyAmygdaloid NucleusAmygdaloid structureAreaBed Nucleus of Stria TerminalisBehaviorBrainBrain Nervous SystemBrain regionCRISPRCRISPR/Cas systemCell BodyCell NucleusCellsChimera ProteinChimeric ProteinsChromatinClustered Regularly Interspaced Short Palindromic RepeatsCoupledDNA RecombinationDREADDsDataDynorphinsEC 2.1.1ElectrophysiologyElectrophysiology (science)EncephalonEnkephalinsEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessEtOH drinkingEtOH useFBJ osteosarcoma oncogeneFOS geneFusion ProteinFutureG0S7Gene ExpressionGene TranscriptionGenesGeneticGenetic RecombinationGenetic TranscriptionGoalsGrantGuide RNAK channelKnowledgeLinkLiteratureMediatingMessenger RNAMethodsMethyltransferaseMiceMice MammalsModelingMurineMusNerve CellsNerve UnitNeural CellNeurocyteNeuronsNeurophysiology / ElectrophysiologyNucleusNucleus AccumbensOrganPathway interactionsPatientsPlayPopulationPositionPositioning AttributePotassium ChannelPotassium Ion ChannelsProtooncogene FOSRNA ExpressionRecombinationRoleSaccharoseSolventsStressStria Terminalis NucleusStructure of terminal stria nuclei of preoptic regionSubstance Use DisorderSucroseSystemTechnologyTestingThree-Dimensional ImagingTranscriptionViral VectorVirusalcohol behavioralcohol induced behavioralcohol ingestionalcohol intakealcohol product usealcohol related behavioralcohol usealcohol use disorderalcoholic beverage consumptionalcoholic drink intakeamygdaloid nuclear complexc fosc-fos Genec-fos Proto-Oncogenescell typedesigner receptors exclusively activated by designer drugsdrinkingelectrophysiologicalepigenetic regulationepigeneticallyethanol behaviorethanol consumptionethanol drinkingethanol induced behaviorethanol ingestionethanol intakeethanol product useethanol related behaviorethanol useethanol use disorderexperimentexperimental researchexperimental studyexperimentsgRNAhistone H3 methyltransferasehistone methylasehistone methyltransferaseinnovateinnovationinnovativeknock-downknockdownmRNAmethylasemultiomicsmultiple omicsneuronalnew drug targetnew druggable targetnew pharmacotherapy targetnew therapeutic targetnew therapy targetnovelnovel drug targetnovel druggable targetnovel pharmacotherapy targetnovel therapeutic targetnovel therapy targetoverexpressoverexpressionpanomicspathwayshRNAshort hairpin RNAsmall hairpin RNAsocial rolestemstress reductionsubstance use and disordertooltransmethylasev-FOS FBJ Murine Osteosarcoma Viral Oncogene Homolog
Description preview
Epigenetic Regulation of Stress-Potentiated Ethanol Drinking
PROJECT SUMMARY/ABSTRACT
A common mechanism that regulates both stress-sensitivity and alcohol use is epigenetic regulation of gene
transcription. Of particular importance in substance-use disorders is G9a, a histone methyltransferase implicated
in models of alcohol use disorder (AUD).…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click