grant

Elucidating the high and heterogeneous risk of gestational diabetes among Asian Americans: an integrative approach of metabolomics, lifestyles, and social determinants

Organization UNIVERSITY OF CALIFORNIA LOS ANGELESLocation LOS ANGELES, UNITED STATESPosted 24 Sept 2023Deadline 30 Apr 2028
NIHUS FederalResearch GrantFY2025Abdominal obesityAcculturationAlpha-1-FetoproteinAlpha-FetoglobulinAndroid fat distributionAsianAsian AmericansAsian groupAsian individualAsian peopleAsian populationAsiansBiologicalBlood SerumCaliforniaCaucasian FemalesCaucasian WomenCentral obesityCentripetal obesityChineseClinicalCohort StudiesConcurrent StudiesCultural AssimilationDataDiagnosisDietDisparitiesDisparityDysfunctionElectronic Health RecordEnvironmentEpidemiologic ResearchEpidemiologic StudiesEpidemiological StudiesEpidemiology ResearchEthnic GroupEthnic OriginEthnic PeopleEthnic PopulationEthnic individualEthnicityEthnicity PeopleEthnicity PopulationFetuinsFilipinoFoodFunctional disorderGestationGestational DiabetesGestational Diabetes MellitusGoalsHealthHeterogeneityHigh PrevalenceIndividualJapaneseKnowledgeLanguageLife StyleLifestyleMediatingMetabolicMetabolic PathwayMolecularNational Institutes of HealthNeighborhoodsNon-HispanicNonhispanicNot Hispanic or LatinoParticipantPathway interactionsPhysical activityPhysiopathologyPopulationPregnancyPregnancy ComplicationsPregnancy-Induced DiabetesPrevalencePreventative strategyPreventionPrevention strategyPreventive strategyProspective cohortPublic Health PracticeRacial GroupResearchResearch ResourcesResourcesRiskRisk FactorsRoleSample SizeSamplingSerumSleepSocial EnvironmentSocioeconomic FactorsSocioeconomically disadvantagedSurvey InstrumentSurveysTruncal obesityUnited StatesUnited States National Institutes of HealthValidationVietnameseWhite FemalesWhite WomenWomanWorkbiologicbuilt environmentcohortcomplications during pregnancycost efficientdeprivationdesigndesigningdiabetes controldiabetes mellitus controldietsdisparities in racedisparity due to racedisparity in ethnicearly in pregnancyearly pregnanciesearly pregnancyearly stage of pregnancyelectronic health care recordelectronic health medical recordelectronic health plan recordelectronic health registryelectronic medical health recordepidemiologic investigationepidemiology studyethnic based disparityethnic disadvantageethnic disparityethnic inequalityethnic inequityethnic subgroupethnicity disparityethnicity grouphealth datahealth equalityhigh riskimprove minority healthimprovement of minority healthindividualized preventioninequality due to raceinequity due to racelife-style factorlifestyle factorsmetabolism measurementmetabolomicsmetabonomicsmid-pregnancynovelpathophysiologypathwaypersonalized preventionprecision preventionpregnancy diabetespregnancy-related complicationspregnantprogramsrace based disparityrace based inequalityrace based inequityrace disparityrace related disparityrace related inequalityrace related inequityracial disparityracial inequalityracial inequityracial populationracial subgroupracially unequalscreening programsegregationsocial climatesocial contextsocial determinantssocial health determinantssocial rolesocio-economic disadvantagesocio-economic factorssocio-economically disadvantagedsocio-economically underprivilegedsociodeterminantsocioeconomic disadvantagesocioeconomically underprivilegedsocioenvironmentsocioenvironmentalsystematic reviewtooltreatment strategyvalidationsvisceral obesityα-Fetoproteins
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PROJECT SUMMARY/ABSTRACT
Gestational diabetes mellitus (GDM), one of the most common and growing complications in pregnancy,

presents striking racial and ethnic disparities. Asian American women are twice as likely to have GDM as non-

Hispanic White women and there is also substantial heterogeneity in GDM rates across Asian subpopulations.

The…

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Elucidating the high and heterogeneous risk of gestational diabetes among Asian Americans: an integrative approach of me | Dev Procure