grant
Elucidating how the PrimPol DNA damage tolerance pathway is regulated and where it operates in human cells
Organization UKRILocation United Kingdom
UKRIUK ResearchGrantActive
Description preview
Cells produce enzymes called DNA polymerases responsible for "photocopying" the genome, which encodes the cell's biological blueprint. Polymerases are frequently stalled by genetic obstacles caused by DNA damage or structures on the template being replicated, leading to defective DNA copying or the formation of mutations that can lead to…
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