grant
Effort-Based Decision Making and Motivated Behavior in Everyday Life
Organization WASHINGTON UNIVERSITYLocation SAINT LOUIS, UNITED STATESPosted 1 Apr 2023Deadline 31 Jan 2028
NIHUS FederalResearch GrantFY2025AddressAffectiveAffective DisordersAnhedoniaAwardBehavioralBehavioral ParadigmBipolar Affective PsychosisBipolar DisorderCausalityCognitionCognitiveCognitive DisturbanceCognitive ImpairmentCognitive declineCognitive function abnormalCorpus StriatumCorpus striatum structureDataDecision MakingDevelopmentDissociationDisturbance in cognitionDopamineDorsalEcological momentary assessmentEtiologyFundingHydroxytyramineImageImpaired cognitionImpairmentIndividualLearningLifeLinkLiteratureMajor Depressive DisorderManic-Depressive PsychosisMeasuresMedialMental DepressionMethodsMood DisordersMoodsMotivationNational Institutes of HealthParietalPathologyPathway interactionsPatient Self-ReportPersonsPositive ValencePrefrontal CortexProcessProgress ReportsPsychosesPsychotic DisordersPublic HealthQOLQuality of lifeRDoCReportingResearchResearch Domain CriteriaRewardsRoleSamplingSchizoaffective DisordersSchizophreniaSchizophrenic DisordersScienceSelf-ReportSocial FunctioningSocial Support SystemStriate BodyStriatumSupport SystemSymptomsSystemTestingTimeUnited States National Institutes of HealthWorkbipolar affective disorderbipolar diseasebipolar illnessbipolar mood disordercausationclinical depressioncognitive assessmentcognitive controlcognitive dysfunctioncognitive losscognitive systemcognitive testingcostdementia praecoxdepressiondepressive psychosisdevelopmentaldisease causationfunction sociallyfunctioning socialgoal oriented behaviorimagingindexinginnovateinnovationinnovativemajor depressionmajor depression disordermanic depressive disordermanic depressive illnessmobile computingmobile platformmobile sensingmobile technologymotivated behaviorneuralneural imagingneural mechanismneuro-imagingneuroimagingneurological imagingneuromechanismneuromelaninnovelpathwaypleasureprogramspsychologicpsychologicalpsychoticpsychotic depressionpsychotic illnessrecruitresponseschizophrenicsocialsocial rolestriatalsystems researchwillingness
Description preview
Motivational impairments are a key feature of both psychotic and mood disorders. Decreases in motivation
impair work and social function transdiagnostically, reduce quality of life, and increase public health demands.
Current treatments are not sufficiently effective at reducing impairments in motivation, in part due to the need
to better…
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