grant

Effects of older age on the neural basis of memory generalization

Organization UNIVERSITY OF WISCONSIN MILWAUKEELocation MILWAUKEE, UNITED STATESPosted 15 Jan 2026Deadline 31 Dec 2030
NIHUS FederalResearch GrantFY202618 year old18 years of ageAffectAgeAgingAmmon HornAppleAssociation LearningAssociative LearningBehaviorBehavioralBrainBrain Nervous SystemBrain regionCognitiveCornu AmmonisDataDecision MakingDrugsEncephalonFailureFoodFunctional MRIFunctional Magnetic Resonance ImagingGleanGoalsHealthHippocampusInstructionInterventionKnowledgeLabelLearningLightMalus domesticaMeasuresMedicationMemoryMemory DeficitMemory impairmentPatientsPavlovian conditioningPerformancePharmaceutical PreparationsPhotoradiationPrefrontal CortexReadingRetrievalRiskRoleSpecificityStomachSystemTestingVariantVariationVisual CortexWorkadjudicationadjudicative process and procedureadult youthage 18age 18 yearsage associated differenceage associated effectsage based differenceage dependent differenceage dependent variationage differenceage effectage related differenceage related effectsage related variationage specific differenceagedagesaging effectassociative conditioningbehavior studybehavioral studyclassical conditioningcognitive abilityconflict resolutiondiffer by agedifference across agedifference in agedrug/agenteffective interventioneighteen year oldeighteen years of ageelderly patientexperienceexperimentexperimental researchexperimental studyexperimentsfMRIgastrichippocampalimpact of ageindexinginfluence of ageinsightmembermemory dysfunctionneuralnovelold ageolder adultolder adulthoodolder patientpreservationpreventpreventingrecruitresponseside effectsocial roletheoriesvariation by agevisual corticalyoung adultyoung adult ageyoung adulthood
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PROJECT SUMMARY
Integration is a key memory ability that allows us to generalize across experiences to make inferences and

accumulate knowledge. For example, your doctor might tell you to take a new medication with food, and you

might later read on the label that the medication can cause an upset stomach. Integrating these memories leads

to the…

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Effects of older age on the neural basis of memory generalization — UNIVERSITY OF WISCONSIN MILWAUKEE | UNITED STATES | | Dev Procure