grant
Dynamic pattern formation in the cell cortex
Organization UNIVERSITY OF WISCONSIN-MADISONLocation MADISON, UNITED STATESPosted 15 Feb 2025Deadline 31 Jan 2030
NIHUS FederalResearch GrantFY2025BehaviorBiologicalBiological FunctionBiological ProcessCell BodyCell Communication and SignalingCell Growth in NumberCell LocomotionCell MigrationCell MovementCell MultiplicationCell ProliferationCell ShapeCell SignalingCell divisionCell membraneCellsCellular MatrixCellular MigrationCellular MotilityCellular ProliferationCytoplasmic MembraneCytoskeletal SystemCytoskeletonDevelopmentDiseaseDisorderGTP PhosphohydrolasesGTPasesGuanosine Triphosphate PhosphohydrolasesGuanosinetriphosphatasesIntracellular Communication and SignalingInvertebrataInvertebratesMedicalMetastasisMetastasizeMetastatic LesionMetastatic MassMetastatic NeoplasmMetastatic TumorMorphogenesisMotor CellMotor NeuronsNeoplasm MetastasisOrganismPathologyPatternPattern FormationPeriodicalsPhysiologic pulsePlasma MembraneProcessPulseSecondary NeoplasmSecondary TumorSignal TransductionSignal Transduction SystemsSignalingTrainingVertebrate AnimalsVertebratesWorkbiologicbiological signal transductioncancer metastasiscell cortexcell motilitydevelopmentalextracellularguanosinetriphosphatasehealinginsightintracellular skeletonliving systemmorphogenetic processmotoneuronperiodicperiodicalplasmalemmarepairrepairedresponserho G-Proteinsrho GTP-Binding Proteinsrho GTPasesrho Protein P21rho Small GTP-Binding Proteinsself organizationtissue repairtooltumor cell metastasisvertebrata
Description preview
Project Summary
The cell cortex--the outermost part of the cell including the plasma membrane and the
underlying cytoskeleton--is extraordinarily important for living systems. As the boundary
between the inside and outside of the cell, it must respond to an enormous variety of
intracellular and extracellular signals; as the primary motor of cell…
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