grant
Dyadic Sleep, Biobehavioral Rhythms and Cognitive Function in Older Adults: Implications for Alzheimer’s Disease
Organization UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAHLocation SALT LAKE CITY, UNITED STATESPosted 1 Apr 2023Deadline 31 Mar 2028
NIHUS FederalResearch GrantFY202521+ years oldAD dementiaAD related dementiaADRDActive Follow-upAddressAdultAdult HumanAffectAlzheimer Type DementiaAlzheimer disease dementiaAlzheimer risk factorAlzheimer sclerosisAlzheimer syndromeAlzheimer'sAlzheimer's DiseaseAlzheimer's and related dementiasAlzheimer's dementia and related dementiaAlzheimer's dementia or related dementiaAlzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease or a related dementiaAlzheimer's disease or a related disorderAlzheimer's disease or related dementiaAlzheimer's disease related dementiaAlzheimer's disease riskAlzheimers DementiaBehaviorBiologicalCell PhoneCellular PhoneCellular TelephoneCessation of lifeCircadian DysregulationCircadian RhythmsCognitionCognitiveCognitive DisturbanceCognitive ImpairmentCognitive declineCognitive function abnormalCouplesDeathDevelopmentDisturbance in cognitionFunctional impairmentHealthHealth Care CostsHealth CostsHealth ExpendituresHealth behaviorImpaired cognitionImpairmentIndividualInterventionLifeMarried PersonsMeasuresMemoryMobile PhonesMoodsNeuropsychologiesNeuropsychologyNyctohemeral RhythmOutcomePatient Self-ReportPatientsPatternPersonal SatisfactionPhysiologyPopulationPremature MortalityPrimary Senile Degenerative DementiaProcessProspective StudiesProtocolProtocols documentationQOLQuality of lifeResearchRestRiskRisk ReductionRoleSamplingSelf-ReportSleepSleep disturbancesSpousesTwenty-Four Hour RhythmVulnerable PopulationsWomanWorkaberrant sleepactigraphactigraphyactive followupadulthoodalzheimer riskbiobehaviorbiobehavioralbiologiccare givingcaregivingcircadiancircadian abnormalitycircadian disruptioncircadian disturbancecircadian dysfunctioncircadian impairmentcircadian processcircadian rhythmicitycognitive assessmentcognitive dysfunctioncognitive functioncognitive losscognitive testingdaily biorhythmdaily functioningdementia riskdevelopmentaldisabilitydisrupted sleepdisturbed sleepexecutive controlexecutive functionexperiencefollow upfollow-upfollowed upfollowuphealth care expenditurehealth related behaviorhealthy aginghealthy human agingiPhoneimpaired sleepimprovement on sleepinnovateinnovationinnovativeirregular sleepmedical expendituremembermenmild cognitive disordermild cognitive impairmentmortalityneuropsychologicnovelolder adultolder adulthoodpoor sleepprimary degenerative dementiaprocessing speedprospectivereduce riskreduce risksreduce that riskreduce the riskreduce these risksreduces riskreduces the riskreducing riskreducing the riskresponserisk factor for dementiarisk for dementiarisk-reducingsenile dementia of the Alzheimer typesexsleep disruptionsleep dysregulationsleep improvementsleep patternsleep routinesleep schedulesleep/wake disruptionsleep/wake disturbancesleep/wake patternssmart phonesmartphonesocialsocial culturesocial rolesocio-culturalsocioculturalvulnerable groupvulnerable individualvulnerable peoplewell-beingwellbeing
Description preview
Abstract
Individuals with mild cognitive impairment (MCI) demonstrate cognitive decline without major functional
impairment but also experience a 7-fold increased risk for developing Alzheimer’s disease, a leading cause of
poorer quality of life (QOL), premature mortality, and health care expenditures. Sleep and biobehavioral rhythm
disturbances…
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