grant
Drug Induced Liver Injury Network Data Coordinating Center
NIHUS FederalResearch GrantFY2025AcuteAdverse ExperienceAdverse eventAncillary StudyAreaBiochemicalBiologicalClinicalClinical ResearchClinical StudyCommunication ToolsCoupledDNA FingerprintingDNA ProfilingDNA TypingDataData Coordinating CenterData Coordination CenterData Management ResourcesData Management SystemData SetDiabetes MellitusDiagnosisDrug PrescribingDrug PrescriptionsDrugsEligibilityEligibility DeterminationEnsureFood and Drug AdministrationFutureGenetic DeterminismGenetic FingerprintingsGrantHepatic DisorderHepatotoxic effectHepatotoxicityHerbal dietary supplementHerbal supplementHistologicHistologicallyIncidenceInjury to LiverKidney DiseasesKnowledgeLiver ToxicityLiver diseasesLogisticsManualsMarketingMedicalMedicationMethodsMiningMulti-center studiesMulticenter StudiesNIDDKNational Institute of Diabetes and Digestive and Kidney DiseasesNational Institutes of HealthNatural ProductsNephropathyNon-Prescription DrugsNonprescription DrugsOTC DrugsOver-the-Counter DrugsPatent MedicinesPathogenesisPathway interactionsPatientsPharmaceutical PreparationsPreventionProceduresProcessProductivityProtocol ScreeningPublic HealthReactionRenal DiseaseResearchResearch InfrastructureResearch InstituteRoleStatistical MethodsToxic effect on liver cellsUSFDAUnited StatesUnited States Food and Drug AdministrationUnited States National Institutes of HealthWithdrawalbiologicbiomarker discoveryclinical centerdata managementdesigndesigningdiabetesdiet supplementdietary supplementsdrug induced hepatotoxicitydrug induced liver diseasedrug induced liver injurydrug/agentexperiencefood monitoringfood supply monitoringfood supply surveillancefood surveillancegenetic analysisgenetic determinanthepatic damagehepatic diseasehepatic injuryhepatic toxicityhepatopathyhepatoxicityhigh riskkidney disorderliver damageliver disorderliver injurymedication prescriptionmeetingmeetingsnaturally occurring productnew drug treatmentsnew drugsnew pharmacological therapeuticnew therapeuticsnew therapynext generation therapeuticsnovelnovel drug treatmentsnovel drugsnovel pharmaco-therapeuticnovel pharmacological therapeuticnovel therapeuticsnovel therapynutritional supplementoperationoperationsparticipant enrollmentpathwaypatient enrollmentpatient populationpharmacovigilancepredictive biological markerpredictive biomarkerspredictive markerpredictive molecular biomarkerprescribed medicationquality assurancerecruitrenal disorderresponsesocial rolestatistic methodssupport networkweb sitewebsite
Description preview
ABSTRACT
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has proposed the continuation
of the Drug-Induced Liver Injury Network (DILIN). As described in the RFA, DILIN will be a network composed
of up to 5 Clinical Centers (CCs) with expertise in diagnosis and management of DILI and a Data Coordinating
Center (DCC)…
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