grant
Dissection of Cell Type Specific Contributions to Motor Learning Circuits
Organization UNIV OF MASSACHUSETTS MED SCH WORCESTERLocation WORCESTER, UNITED STATESPosted 15 Jul 2022Deadline 31 Mar 2028
NIHUS FederalResearch GrantFY2025ASDAddressAffectAnimalsAreaAssayAutismAutistic DisorderBehaviorBioassayBiological AssayBrainBrain MappingBrain Nervous SystemBrain regionCAGH44CalciumCell BodyCell NucleusCellsClassificationComplementComplement ProteinsComplexDNA Molecular BiologyData AnalysesData AnalysisDiseaseDisorderDissectionEarly Infantile AutismEncephalonEnvironmentExhibitsFOXP2FOXP2 geneFeedbackForelimbForkhead Box P2Gene Expression MonitoringGene Expression Pattern AnalysisGene Expression ProfilingGene TranscriptionGenerationsGenetic TranscriptionGoalsHumanImmediate-Early GenesIn vivo two-photon calcium imagingInfantile AutismInvestigatorsKanner's SyndromeLearningLearning SkillLifeMapsMedulla SpinalisMentorsModern ManMolecularMolecular BiologyMotorMotor CortexMotor SkillsMovementNerve CellsNerve UnitNeural CellNeurocyteNeuronsNeurosciencesNucleusParalysis AgitansParkinsonParkinson DiseasePatternPhasePhenotypePopulationPopulation HeterogeneityPositionPositioning AttributePrimary ParkinsonismProcessProxyRNA ExpressionRNA SeqRNA sequencingRNAseqReportingResearch PersonnelResearchersRestRoleSkeletal MuscleSortingSpinal ColumnSpinal CordSpineSystemSystematicsTNRC10Thalamic structureThalamusThinkingTrainingTranscript Expression AnalysesTranscript Expression AnalysisTranscriptionTrinucleotide Repeat-Containing Gene 10UniversitiesVertebral columnVoluntary MuscleWorkanalyze gene expressionautism spectral disorderautism spectrum disorderautistic spectrum disorderbackbonebody movementcell imagingcell typecellular imagingcomplementationdata interpretationdiverse populationsgene expression analysisgene expression assayheterogeneous populationimaging approachimaging based approachimaging in vivoin vivoin vivo calcium imagingin vivo imaginglocomotor learningmotor abilitymotor diseasemotor disordermotor dysfunctionmotor learningmotor skill learningneuralneuronalnew approachesnovel approachesnovel strategiesnovel strategyoptogeneticsperceptual motor learningpopulation diversityrecruitresponseskillssocial rolesuccessthalamicthoughtstranscriptional profilingtranscriptome sequencingtranscriptomic sequencingtranscriptomics
Description preview
Project Abstract
Whether riding your bike down a narrow path or reaching for your favorite cookie in a small box, many of our
daily actions require skilled and accurate movements. However, to achieve proficiency, these motor skills must
first be learned through the process of motor learning. Much work on this subject has focused on the dynamics
of…
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