Dissecting the role interneuron dysfunction in Neurofibromatosis type I

Neurofibromatosis type 1 (NF1) is a commonly inherited neurological disease that affects around 1:2700 individuals1. Around 50-60% of these individuals will have some form of cognitive dysfunction. Consequently, as a monogenic neurodevelopmental disorder with high cognitive dysfunction penetrance, NF1 presents an invaluable avenue in understanding…