grant
DIRECTED EVOLUTION OF BIOCATALYSTS FOR ASYMMETRIC HYDROGEN ATOM TRANSFER REACTIONS
Organization UNIVERSITY OF CALIFORNIA LOS ANGELESLocation LOS ANGELES, UNITED STATESPosted 1 Mar 2026Deadline 28 Feb 2031
NIHUS FederalResearch GrantFY2026AccelerationAlkenesBiochemistryBioinorganic ChemistryBiological ChemistryCarbonChemistryComplexComputer ModelsComputerized ModelsDevelopmentDirected Molecular EvolutionEngineeringFutureH elementHealthHumanHydrogenInterdisciplinary ResearchInterdisciplinary StudyMediatingMetalsMethodsModern ManMultidisciplinary CollaborationMultidisciplinary ResearchOlefinsOrganic ChemistryPharmaceutical AgentPharmaceuticalsPharmacologic SubstancePharmacological SubstanceProcessProductionProtein EngineeringReactionResearchSynthesis ChemistrySynthetic Chemistrycatalystchiral moleculecomputational modelingcomputational modelscomputer based modelscomputerized modelingdesigndesigningdevelopmentaldirected evolutiondrug discoveryfrontiergenetic protein engineeringimprovedpharmaceuticalprogramsprotein designrational designtool
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Project Summary
The rise of biocatalysis is transforming synthetic chemistry by enabling highly selective and sustainable
transformations. Despite advances, achieving precise stereocontrol in radical-mediated reactions remains a
significant frontier. This interdisciplinary research program integrates expertise in organic chemistry, protein…
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