grant
DIALS: supporting structural biology through open source diffraction processing software
Organization UNIVERSITY OF CALIF-LAWRENC BERKELEY LABLocation BERKELEY, UNITED STATESPosted 20 Sept 2024Deadline 31 Jul 2029
NIHUS FederalResearch GrantFY2025AccelerationAchievementAchievement AttainmentAddressAdoptionAdvisory CommitteesBiologicalCOVID-19CV-19Cell Communication and SignalingCell SignalingCodeCoding SystemCollaborationsCommunitiesComputer Software ToolsComputer softwareCoronavirus Infectious Disease 2019CrystallographiesCrystallographyDataData AnalysesData AnalysisData CollectionData FilesData SetDecision MakingDependenceDesigning computer softwareDevelopmentDevelopment and ResearchDiamondDiseaseDisease ProgressionDisorderDocumentationDrug DesignEducation and OutreachEnsureEnvironmentExposure toFeedbackFundingFutureGoalsGraphical interfaceHealthHumanImageIndividualInstruction and OutreachInternationalInterventionIntracellular Communication and SignalingInvestigatorsLibrariesLifeLightMaintenanceMalariaMemoryModern ManMolecularOutcomePaludismPatternPerformancePhasePhotoradiationPhotosynthesisPlasmodium InfectionsPositionPositioning AttributeProcessProgress ReportsProteinsPythonsR & DR&DR24ReadingResearchResearch PersonnelResearch ResourcesResearchersResourcesRoentgen RaysScheduleScientistSignal TransductionSignal Transduction SystemsSignalingSingle Crystal DiffractionSiteSoftwareSoftware DesignSoftware ToolsSourceSpeedStructureSynchrotronsSystemTask ForcesTechnologyTestingTrainingTraining and OutreachTutoring and OutreachUpdateVaccinesWritingX Ray CrystallographiesX-RadiationX-Ray CrystallographyX-Ray Diffraction CrystallographyX-Ray RadiationX-Ray/Neutron CrystallographyX-rayXrayXray CrystallographyXray free electron laseradvisory teambasebasesbeamlinebiologicbiological signal transductioncluster computingcombatcomputerized data processingcoronavirus disease 2019coronavirus disease-19coronavirus infectious disease-19data archivedata archivesdata griddata interpretationdata processingdata qualitydatagriddesigndesigningdetectordevelopmentaldisease controldisorder controldistributed computingexperimentexperimental researchexperimental studyexperimentsfile formatflexibilityflexiblegraphic user interfacegraphical user interfacehuman diseaseimagingimprovedlarge data setslarge datasetsopen sourceoperationoperationsportabilityprogramsprotein structureprotein structuresproteins structureresearch and developmentsoftware toolkitsoftware user interfacestructural biologytech developmenttechnology developmenttoolx-ray FELx-ray free-electron laser
Description preview
Project Summary/Abstract
X-ray crystallography is a powerful tool for determining the atomic positions of proteins, used by researchers at
synchrotrons and X-ray free electron lasers. Typically, the crystal is exposed to X-rays, which diffract and are
collected on a detector to create diffraction patterns. These patterns are processed by software…
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