grant

Diagnostics Core

Organization TUFTS UNIVERSITY BOSTONLocation BOSTON, UNITED STATESPosted 5 Sept 2024Deadline 30 Jun 2029
NIHUS FederalResearch GrantFY202519S Gamma GlobulinAI systemAdherenceAliquotAntibodiesAntibody ResponseAnticoagulationArchivesArtificial IntelligenceAssayBayesian AnalysisBayesian computationBayesian inferenceBayesian network analysisBayesian spatial analysisBayesian statistical analysisBayesian statistical inferenceBayesian statisticsBioassayBiological AssayBiopsy SampleBiopsy SpecimenBlood PlasmaBlood SampleBlood SerumBlood TestsBlood specimenBorreliaCLIA accreditedCLIA approvedCLIA certifiedCLIA compliantCLIA licensedChemistryClinicalClinical MicrobiologyComplementComplement ProteinsComputer ReasoningDataData AnalysesData AnalysisData SetDecision TheoryDermatologic biopsyDevelopmentDiagnosticDiagnostic MethodDiagnostic ProcedureDiagnostic Reagent KitsDiagnostic TechniqueDiagnostic testsEDTAEdathamilEdetic AcidEnrollmentEnsureEthylenediaminetetraacetic AcidEthylenedinitrilotetraacetic AcidEvaluationExperimental DesignsFreezingGeneral HospitalsGoalsHematologic TestsHematological TestsHematologyHematology TestingHumanIgMImmunoglobulin MIndividualInfectious AgentInvestigationInvestigatorsIxodesIxodes tickLaboratoriesLesionLyme BorreliosisLyme DiseaseMachine IntelligenceMachine LearningMapsMassachusettsMethodologyMethodsModelingModern ManPBMCPathogen detectionPatientsPerformancePeripheral Blood Mononuclear CellPlasmaPlasma SerumPositionPositioning AttributePost Treatment Lyme Disease SyndromePowassanPowassan virusProceduresProcessProspective StudiesProtocolProtocols documentationRectumReproducibilityResearchResearch PersonnelResearch SupportResearchersReticuloendothelial System, Serum, PlasmaRunningSamplingSerologySerumServicesStandardizationSwabSystemTest ResultTestingTick-Borne InfectionsUrineVisitWhole Bloodadjudicationadjudicative process and procedurebiobankbiorepositoryborrelialchronic symptomclinical careclinical research siteclinical sitecohortcold temperaturecomplementationcomputer based predictioncutaneous biopsydata integrationdata interpretationdevelopmentaldiagnostic kitenrollerythema migransexperiencefallshuman subjectinfectious organismlow temperaturemachine based learningmetagenome sequencingmetagenomic sequencingpersistent symptompredictive modelingprogramsprospectiveskin biopsytest kittick-bornetickbornetickborne infection
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ABSTRACT- DIAGNOSTIC CORE
The Diagnostics Core provides comprehensive laboratory testing for Lyme disease in a CLIA-certified clinical

laboratory setting. Its purpose is to provide standardized laboratory services to the Clinical Core, to assist in

characterizing enrolled subjects, and to provide archived human samples to support the Projects.…

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