grant
Development of obesity and metabolic clinical research programs
Organization NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASESLocation UNITED STATES
NIHUS FederalResearch GrantFY20250-11 years old21+ years old3-D3-Dimensional3DAdrenal Medullary ParagangliomaAdrenal Medullary PheochromocytomaAdrenal PheochromocytomaAdultAdult HumanAfrican AmericanAfro AmericanAfroamericanAgeAgingAgreementAirAmerican maleAmerican manAmerican menAnimalsAreaBasal MetabolismBasal metabolic rateBioelectrical ImpedanceBiolectric ImpedanceBloodBlood Reticuloendothelial SystemBody CompositionBody SizeBody Surface AreaBody TemperatureBody WeightBrown Adipose TissueBrown FatCLN3CLN3 geneCLN3 proteinCaloric IntakeCaloriesCardiac ChronotropismChildChild YouthChildhoodChildren (0-21)Chromaffin NeoplasmChromaffin ParagangliomaChromaffin TumorChronic GVHDClinicalClinical NutritionClinical ProtocolsClinical ResearchClinical StudyClothingContracting OpportunitiesContractsControl GroupsDEXADXADataDietary intakeDiseaseDisorderDoseDrug TherapyDual-Energy X-Ray AbsorptiometryDual-Energy Xray AbsorptiometryEnergy ExpenditureEnergy IntakeEnergy MetabolismEnrollmentEquationEquipmentEthnic OriginEthnicityExpenditureFastingFatsFatty acid glycerol estersFemaleGangliocytic ParagangliomaGoalsHSC transplantationHeart RateHeat ProductionHematopoietic Stem Cell TransplantHematopoietic Stem Cell TransplantationHereditaryHibernating GlandHourHumanIndirect CalorimetryIndividualInheritedInpatientsIntermediary MetabolismIntraadrenal ParagangliomaLaser ElectromagneticLaser RadiationLasersLeannessManuscriptsMeasurementMeasuresMetabolicMetabolic ProcessesMetabolismMethodsModern ManMovementMuscleMuscle TissueNICHDNational Institute of Child Health and Human DevelopmentNatural HistoryNervous SystemNeurologic Body SystemNeurologic Organ SystemNutrition AssessmentNutrition ResearchNutritional AssessmentNutritional StudyObesityOrganParagangliomaParaganglion NeoplasmParaganglion TumorParaganglionic NeoplasmParaganglionic TumorParticipantPatientsPersonsPharmacological TreatmentPharmacotherapyPhasePheochromocytomaPhysical activityPhysiologicPhysiologicalPlethysmographyPopulationProtocolProtocols documentationPublicationsPublishingRaceRacesRandomizedRegulationReproducibilityResearchRespiration CalorimetryRestRoleScanningScientific PublicationShiveringSkeletal MuscleSkinSpectroscopySpectrum AnalysesSpectrum AnalysisSystemTechniquesTemperatureTestingThermogenesisThinnessTimeU.S. MalesUS MenUS maleVariantVariationVoluntary MuscleWeightWomen's cohortadiposityadulthoodagesbiological adaptation to stressblood stem cell transplantationbody movementbonecaloric dietary contentchromaffinomachronic graft versus host diseasechronic graft vs host diseasechronic graft vs. host diseasecohortcohort in womencohort on womencorpulencedesigndesigningdevelopmental diseasedevelopmental disorderdrug interventiondrug treatmentenrollenvironmental changeexperiencefastedfastsfemale cohortfightingfull scale manufacturinghealthy volunteerhematopoietic cell transplantationhematopoietic cellular transplantationhematopoietic progenitor cell transplantationimprovedinsightinstrumentationinterestkidslarge scale manufacturinglarge scale productionmalemales in Americamales in the U.S.males in the USmales in the USAmales in the United Statesmass productionmenmen in Americamen in the U.S.men in the USmen in the USAmen in the United Statesmetabolic ratemilitary operationmuscularnew technologynovel technologiesobesity developmentpediatricpharmaceutical interventionpharmacological interventionpharmacological therapypharmacology interventionpharmacology treatmentpharmacotherapeuticsprogramsracialracial backgroundracial originrandomisationrandomizationrandomly assignedreaction; crisisresponseresting metabolic ratesexskeletal dysplasiasocial rolesoft tissuestable isotopestress responsestress; reactionthree dimensionalurinaryvolunteerweightsyoungster♀♂
Description preview
In FY25, we made progresses in the following areas.
1. We continue to accrue study participants in the natural history protocol (000617 NCT05398783) stated in late FY23. The primary aim is to examine the agreement between measured whole-body surface area (BSA) using our new 3D laser scanner (Vitus) and BSA estimated by previously established…
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