grant
Development of FES+BMI Neuroprosthesis for At-Home Use for Persons with Chronic Tetraplegia
Organization LOUIS STOKES CLEVELAND VA MEDICAL CENTERLocation CLEVELAND, UNITED STATESPosted 1 Oct 2025Deadline 30 Sept 2029
VANIHUS FederalResearch GrantFY2025Active Follow-upActivities of Daily LivingActivities of everyday lifeAffectAlgorithmsAttentionAwarenessBehaviorBiological MarkersBlinkingBlood PressureBrainBrain Nervous SystemCalibrationCausalityCell Communication and SignalingCell SignalingCervical InjuryCervical spinal cord injuryChronicCitiesClinical TrialsClinical assessmentsDevelopmentElectrical Stimulation of the BrainElectrodesElectromyographyEncephalonEnrollmentEtiologyExhibitsExtremitiesFascicleFatigueFrequenciesGripsHandHand functionsHomeHome environmentImplantImplanted ElectrodesIndividualIntracellular Communication and SignalingIntramuscularIntuitionIowaLaboratoriesLack of EnergyLength of LifeLimb structureLimbsLongevityMeasurableMeasuresMembrum superiusMethodsModalityMotorMotor CortexMovementNamesNerveNerve CellsNerve UnitNeural CellNeurocyteNeuronsNon-TrunkOutcome MeasurePalsyParalysedParietal LobeParticipantPatient Self-ReportPerformancePeripheralPeripheral NervesPersonsPhasePhysiologicPhysiologicalPlegiaPopulationProtocolProtocols documentationPupilQuadriplegiaQuadriplegicReportingResearchSaccadesSaccadic Eye MovementsSaccadic PursuitSelf-ReportSignal TransductionSignal Transduction SystemsSignalingSodium ChlorideSpinal Cord TraumaSpinal TraumaSpinal cord injuredSpinal cord injuryStressSurvey InstrumentSurveysSystemTechnologyTestingTetraplegiaThinkingTimeTrainingTranslatingTranslationsTraumatic MyelopathyUpper ExtremityUpper LimbUsing handsUtahVeteransVoiceWorkactive followupadvanced systemarmarm functionarm functionalitybio-markersbiologic markerbiological signal transductionbiomarkerbody movementbrain controlbrain implantbrain machine interfacecausationclinical validationdaily living functiondaily living functionalitydesigndesigningdevelopmentaldisease causationenrolleye blinkeyeblinkfeedingfollow upfollow-upfollowed upfollowupfunctional abilityfunctional capacityfunctional electrical stimulationfunctional electrostimulationfunctional restorationgrasphand grasphandsheart rate variabilityhomesindexinginnovateinnovationinnovativeintuitivelab assignmentlab experiencelab experimentlab traininglaboratory activitylaboratory assignmentlaboratory exerciselaboratory experiencelaboratory experimentlaboratory trainingmeasurable outcomemicrosystemsnamenamednamingneuralneural implantneuro-prostheticneuronalneuroprosthesisneuroprostheticoutcome measurementparalysisparalyticparietal cortexparticipant enrollmentpatient enrollmentportabilityrestorationrestore functionrestore functionalityrestore lost functionsaltsatisfactionsuccesstetraplegicthoughtstranslationvirtual
Description preview
The current proposal aims to develop a for at-home-use neuroprosthesis for restoring brain-controlled
functional hand grasping to Veterans and others living with chronic tetraplegia due to spinal cord injury (SCI).
This system leverages and advances two established technologies – functional-electrical stimulation (FES)
systems for re-animating…
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