grant
Developing computational, experimental and ecological approaches to study integrated phages and their hosts
Organization STANFORD UNIVERSITYLocation STANFORD, UNITED STATESPosted 13 Mar 2026Deadline 31 Jan 2030
NIHUS FederalResearch GrantFY2026AdoptedAffectAlgorithmsArchitectureBacteriaBacterial GenomeBacteriophagesBiologyBionomicsBiophysicsClassificationCollaborationsComputational toolkitComputer ModelsComputerized ModelsComputing MethodologiesDNADataDeoxyribonucleic AcidDevelopmentDevicesEcologyEngineering / ArchitectureEventFecesFrequenciesFunctional MetagenomicsFutureGI microbiomeGeneral TaxonomyGeneralized GrowthGenomeGenomicsGoalsGrowthHarvestHealthHi-CHumanHuman MicrobiomeImmunityIn SituIn VitroIndividualKnowledgeLengthLife CycleLife Cycle StagesLife StyleLifestyleLinkLysogenyLyticMachine LearningMath ModelsMeasuresMetagenomicsMethodsMicrobiomicsModelingModern ManMolecularOpticsOutcomePhagesPlasmidsPlayPopulationPopulation DynamicsProphage IntegrationProphagesResearchResearch ResourcesResourcesRoleSamplingShapesStructureSystematicsTaxonomyTechnologyTestingTherapeuticTimeTissue GrowthViralVirusWorkbacterial virusbiophysical foundationbiophysical principlesbiophysical sciencescandidate identificationclinical applicabilityclinical applicationcommunity microbescomputational frameworkcomputational methodologycomputational methodscomputational modelingcomputational modelscomputational resourcescomputational suitecomputational toolboxcomputational toolscomputational toolsetcomputer based methodcomputer based modelscomputer frameworkcomputer methodscomputerized modelingcomputerized toolscomputing methodcomputing resourcescontigdensitydetectordevelopmentaldigestive tract microbiomeenteric microbiomefecal samplegastrointestinal microbiomegut microbiomegut-associated microbiomehuman-associated microbiomeimprovedinnovateinnovationinnovativeintegration siteinterestintestinal biomeintestinal microbiomelife courselong read seqlong-read sequencinglong-read transcript sequencingmachine based learningmathematic modelmathematical modelmathematical modelingmetagenome sequencingmetagenomic sequencingmicrobe communitymicrobialmicrobial communitymicrobiomemicrobiome researchmicrobiome sciencemicrobiome studiesmicroorganism communitymultidisciplinarynovelontogenyopticalpolymicrobial communitysocial rolestoolstool samplestool specimenstructural mutationstructural variantstructural variationtechnological innovationtool
Description preview
ABSTRACT
Bacteriophages are integral components of the human microbiome, shaping microbial diversity and influencing
host health, yet our understanding of phage-host dynamics remains limited, particularly for integrated phages.
Recent discoveries reveal that lysogenic phages dominate the human gut microbiome over lytic phages, but
current methods…
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