grant

Designer nanodiscs to probe and reprogram membrane biology

Organization UNIVERSITY OF VIRGINIALocation CHARLOTTESVILLE, UNITED STATESPosted 1 Jun 2025Deadline 31 Mar 2030
NIHUS FederalResearch GrantFY2025AutoregulationBiochemicalBiochemical ReactionBody TissuesBypassCell BodyCell CommunicationCell Communication and SignalingCell FunctionCell InteractionCell PhysiologyCell ProcessCell SignalingCell membraneCell surfaceCell-to-Cell InteractionCellsCellular FunctionCellular PhysiologyCellular ProcessCytoplasmic MembraneDevelopmentEnsureEnzymatic ReactionEventGoalsHandHealthHomeostasisHumanHydrogen OxideIntracellular Communication and SignalingIonsLaboratoriesLifeLightLipidsMaintenanceMediatingMembraneMembrane BiologyMembrane FusionMembrane Protein GeneMembrane ProteinsMembrane-Associated ProteinsMethodsModern ManMolecularNanotechnologyOrganellesOrganismPeptidesPhotoradiationPhysiological HomeostasisPhysiologyPlasma MembraneProtein DynamicsProteinsReagentSignal PathwaySignal TransductionSignal Transduction SystemsSignalingStructureSubcellular ProcessSurface ProteinsTissuesWaterbiological signal transductioncell typedevelopmentalexosomefascinatehandsinnovateinnovationinnovativeinsightliving systemmembrane structurenano technano technologynano-technologicalnanodisknanotechnanotechnologicalnext generationnovelplasmalemmaprogramsprotein complextool
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Abstract
Life originates from the enfolding of critical cellular activities by water-impermeable membrane structures. This
compartmentalization is vital to maintain the identity and function of all cells and most organelles. However, the
physical barrier of cell membranes also necessitates the development of sophisticated intercellular signaling…

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Designer nanodiscs to probe and reprogram membrane biology — UNIVERSITY OF VIRGINIA | UNITED STATES | Jun 2025 | Dev Procure