grant
Decoding cell surface chemistry and function in Staphylococcus aureus
Organization STANFORD UNIVERSITYLocation STANFORD, UNITED STATESPosted 1 Aug 2025Deadline 31 Jul 2030
NIHUS FederalResearch GrantFY2025AnionsAnti-Infective AgentsAnti-Infective DrugsAnti-InfectivesAnti-infective PreparationAntibiotic AgentsAntibiotic DrugsAntibioticsAntimicrobial ResistanceArchitectureAreaBacteriaBiochemistryBiological ChemistryBlind SpotsBody TissuesCell BodyCell WallCell surfaceCell-Extracellular MatrixCellsCelluloseChemical StructureChemicalsChemistryCommunitiesDetectionDevelopmentDiseaseDisorderE coliE. coliECMEngineering / ArchitectureEscherichia coliExhibitsExtracellular MatrixFriendsGlycansGlycoconjugatesHealthHost DefenseHumanLabelLaboratoriesMicrobial BiofilmsMicroscopyMiscellaneous AntibioticModern ManModificationMolecularMureinNasalNasal Passages NoseNatureNoseOrganismPeptidesPeptidoglycanPolyanhydroglucuronic AcidPolymersPolysaccharidesProliferatingProteinsProteomicsResearchResistanceRespiratory System, Nose, Nasal PassagesRetinal blind spotS aureusS. aureusSSNMRSkinStaph aureusStaphylococcus aureusTeichoic AcidsTissuesVancomycinVirulenceWorkalpha-Celluloseanti-microbialanti-microbial resistantantibiotic resistant infectionsantimicrobialbacteria pathogenbacterial pathogenbiofilmcommunicable disease control agentdesigndesigningdetection methoddetection proceduredetection techniquedevelopmentalgut healthinstrumentationliving systemmicrobiomemodel organismpathogenpathogenic bacteriapolymerpolymericpreventpreventingprogramsresistance to anti-microbialresistantresistant to antimicrobialsolid state NMRsolid state nuclear magnetic resonancetranscriptomics
Description preview
PROJECT SUMMARY
Bacteria are essential to human health and also one of our greatest threats. Bacteria in the microbiome
facilitate gut health and prevent proliferation of unwanted organisms. However, pathogenic bacteria damage
tissues and enmesh themselves in communities termed biofilms that evade antimicrobials and host defenses.
The unique…
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