grant

Culturally adapted mobile treatment of chronic pain in adolescent survivors of pediatric bone sarcoma

Organization ST. JUDE CHILDREN'S RESEARCH HOSPITALLocation MEMPHIS, UNITED STATESPosted 20 Sept 2022Deadline 31 May 2028
NIHUS FederalResearch GrantFY20250-11 years old12-20 years old21+ years oldAccess to CareActive Follow-upAddressAdolescenceAdolescentAdolescent YouthAdultAdult HumanAffectiveAnalgesic AgentsAnalgesic DrugsAnalgesic PreparationAnalgesicsAnodynesAntinociceptive AgentsAntinociceptive DrugsAnxietyAreaBehaviorBlackBlack PopulationsBlack groupBlack individualBlack peopleBlack raceBlacksBone SarcomaBone TumorBone neoplasmsBrain regionCancer SurvivorChildChild YouthChildhoodChildren (0-21)Children's Oncology GroupCognition TherapyCognitiveCognitive DiscriminationCognitive PsychotherapyCognitive TherapyCognitive treatmentDevelopmentDiagnosisDiscriminationDiseaseDisorderDisparitiesDisparityEffectivenessEmotionalEmotional DepressionEthnic GroupEthnic OriginEthnic PeopleEthnic PopulationEthnic individualEthnicityEthnicity PeopleEthnicity PopulationEwing's Family of TumoursEwing's Sarcoma/Peripheral Primitive Neuroectodermal TumorEwing's TumorEwings sarcomaFaceFatigueFeedbackFutureGeneral PopulationGeneral PublicGeographyHealth Services AccessibilityHigh PrevalenceHispanicHispanic PopulationsHispanic groupHispanic individualHispanic peopleHispanicsImpairmentIncidenceInterventionLack of EnergyLong-Term SurvivorsMalignant Soft Tissue NeoplasmMental DepressionMental HealthMental HygieneNeurocognitionNon-HispanicNon-pharmacologic TherapyNonhispanicNonpharmacologic InterventionNonpharmacologic TherapyNonpharmacologic approachNonpharmacologic treatmentNot Hispanic or LatinoOperative ProceduresOperative Surgical ProceduresOsseous NeoplasmOsseous SarcomaOsseous TumorOsteogenic SarcomaOsteosarcomaOutcomePainPain ControlPain TherapyPain intensityPain managementPainfulParentsPatientsPediatric Oncology GroupPhasePhysical FunctionPlacebosPopulationPopulation HeterogeneityPrefrontal CortexPrevalenceProceduresPsychological HealthQOLQuality of lifeRaceRacesRacial GroupRandomizedReportingResearchRiskSamplingSarcomaSensorySham TreatmentSiteSkeletal SarcomaSleepSocial FunctioningStructural RacismSupportive TherapySupportive careSurgicalSurgical InterventionsSurgical ProcedureSurvivorsTherapeutic InterventionThinkingTimeToxic effectToxicitiesTreatment EfficacyUnderserved PopulationYouthYouth 10-21access to health servicesaccess to servicesaccess to treatmentaccessibility to health servicesactive followupadolescence (12-20)adulthoodassociated symptomavailability of servicesbasebasescancer carecare accesschildhood cancer survivorchildhood sarcomachronic painchronic pain controlchronic pain interventionchronic pain managementchronic pain therapychronic pain treatmentco-morbidco-morbid symptomco-morbidityco-occuring symptomcognitive behavior interventioncognitive behavior modificationcognitive behavior therapycognitive behavioral interventioncognitive behavioral modificationcognitive behavioral therapycognitive behavioral treatmentcomorbid symptomcomorbidityconcurrent symptomcooccuring symptomcurative interventioncurative therapeuticcurative therapycurative treatmentsdaily functioningdelivered remotelydepressiondepression symptomdepressivedepressive symptomsdeprivationdetermine efficacydevelopmentaldifferences due to racedifferences in racediffers by racediffers in racedisparities in racedisparity due to racedisparity in ethnicdiverse populationsefficacy analysisefficacy assessmentefficacy determinationefficacy evaluationefficacy examinationethnic based disparityethnic differenceethnic disadvantageethnic disparityethnic diversityethnic inequalityethnic inequityethnic subgroupethnically diverseethnicity differenceethnicity disparityethnicity groupevaluate efficacyevidence baseexamine efficacyexperiencefacesfacialfollow upfollow-upfollowed upfollowupfunction sociallyfunctional disabilityfunctioning socialhealth service accesshealth services availabilityheterogeneous populationhigh riskimplementation strategyimplementation trialimprovedindexinginequality due to raceinequity due to raceintervention efficacyintervention therapyjuvenilejuvenile humankidsmalignant soft tissue tumormembermortalitynon-drug therapynon-drug treatmentnondrug therapynondrug treatmentopiate consumptionopiate drug useopiate intakeopiate useopioid consumptionopioid drug useopioid intakeopioid useosteochondrosarcomaosteoid sarcomapain interventionpain killerpain medicationpain processingpain relieverpain treatmentpainkillerparentpatient populationpediatricpediatric cancer survivorpediatric sarcomaphysical conditioningphysical healthpopulation diversitypost interventionprogramsquality of sleeprace based differencesrace based disparityrace based inequalityrace based inequityrace differencesrace disparityrace related differencesrace related disparityrace related inequalityrace related inequityracialracial backgroundracial differenceracial disparityracial diversityracial inequalityracial inequityracial originracial populationracial subgroupracially differentracially diverseracially unequalrandomisationrandomizationrandomized, clinical trialsrandomly assignedremote deliveryremote interventionservice availabilitysham therapysleep qualitysocial health determinantsstandard of carestrategies for implementationsurgerysurvivorshipsymptom associationsymptom comorbiditytherapeutic efficacytherapy efficacythoughtstranscranial direct current stimulationtreat chronic paintreatment accessunder served groupunder served individualunder served peopleunder served populationunderserved groupunderserved individualunderserved peopleuptakeyoungsteryouth age
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ABSTRACT
More than 70% of children and adolescents diagnosed with a bone sarcoma now survive at least five years post-

diagnosis. Unfortunately, curative treatments result in toxicities that leave many survivors with a substantial

burden of adverse physical and mental health outcomes, including chronic pain. Up to 59% of long-term survivors

report…

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